Cytoplasmic Retention of a Nucleocytoplasmic Protein TBC1D3 by Microtubule Network Is Required for Enhanced EGFR Signaling

The hominoid oncogene TBC1D3 enhances epidermal growth factor receptor (EGFR) signaling and induces cell transformation. However, little is known regarding its spatio-temporal regulation and mechanism of tumorigenesis. In the current study, we identified the microtubule subunit β-tubulin as a potent...

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Detalles Bibliográficos
Autores principales: He, Ze, Tian, Tian, Guo, Dan, Wu, Huijuan, Chen, Yang, Zhang, Yongchen, Wan, Qing, Zhao, Huzi, Wang, Congyang, Shen, Hongjing, Zhao, Lei, Bu, Xiaodong, Wan, Meiling, Shen, Chuanlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979746/
https://www.ncbi.nlm.nih.gov/pubmed/24714105
http://dx.doi.org/10.1371/journal.pone.0094134

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