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An Oxidative Stress Mechanism of Shikonin in Human Glioma Cells

Shikonin is a quinone-containing natural product that induces the apoptotic death of some cancer cell lines in culture through increasing intracellular reactive oxygen species (ROS). Quinone-based drugs have shown potential in the clinic, making shikonin an interesting compound to study. Our previou...

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Detalles Bibliográficos
Autores principales: Yang, Jen-Tsung, Li, Zih-Ling, Wu, Jin-Yi, Lu, Fung-Jou, Chen, Ching-Hsein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979747/
https://www.ncbi.nlm.nih.gov/pubmed/24714453
http://dx.doi.org/10.1371/journal.pone.0094180