Cargando…
BMP Pathway Regulation of and by Macrophages
Pulmonary arterial hypertension (PAH) is a disease of progressively increasing pulmonary vascular resistance, associated with mutations of the type 2 receptor for the BMP pathway, BMPR2. The canonical signaling pathway for BMPR2 is through the SMAD family of transcription factors. BMPR2 is expressed...
Autores principales: | Talati, Megha, West, James, Zaynagetdinov, Rinat, Hong, Charles C., Han, Wei, Blackwell, Tom, Robinson, Linda, Blackwell, Timothy S., Lane, Kirk |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979749/ https://www.ncbi.nlm.nih.gov/pubmed/24713633 http://dx.doi.org/10.1371/journal.pone.0094119 |
Ejemplares similares
-
Oxidative injury is a common consequence of BMPR2 mutations
por: Lane, Kirk L., et al.
Publicado: (2011) -
Gas6/MerTK signaling is negatively regulated by NF-κB and supports lung carcinogenesis
por: Novitskiy, Sergey V., et al.
Publicado: (2019) -
Correction: BMP Pathway Regulation of and by Macrophages
Publicado: (2014) -
Chronic NF-κB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs
por: Zaynagetdinov, Rinat, et al.
Publicado: (2015) -
Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension
por: West, James, et al.
Publicado: (2020)