CD8(+) Regulatory T Cells, and Not CD4(+) T Cells, Dominate Suppressive Phenotype and Function after In Vitro Live Mycobacterium bovis-BCG Activation of Human Cells

Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG), the only currently available vaccine against tuberculosis, has been reported to induce regulatory T cells in humans. The activity of regulatory T cells may not only dampen immunogenicity and protective efficacy of tuberculosis-vaccines, bu...

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Detalles Bibliográficos
Autores principales: Boer, Mardi C., van Meijgaarden, Krista E., Joosten, Simone A., Ottenhoff, Tom H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979753/
https://www.ncbi.nlm.nih.gov/pubmed/24714620
http://dx.doi.org/10.1371/journal.pone.0094192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979753/
https://www.ncbi.nlm.nih.gov/pubmed/24714620
http://dx.doi.org/10.1371/journal.pone.0094192

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