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CD8(+) Regulatory T Cells, and Not CD4(+) T Cells, Dominate Suppressive Phenotype and Function after In Vitro Live Mycobacterium bovis-BCG Activation of Human Cells

Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG), the only currently available vaccine against tuberculosis, has been reported to induce regulatory T cells in humans. The activity of regulatory T cells may not only dampen immunogenicity and protective efficacy of tuberculosis-vaccines, bu...

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Detalles Bibliográficos
Autores principales:	Boer, Mardi C., van Meijgaarden, Krista E., Joosten, Simone A., Ottenhoff, Tom H. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979753/ https://www.ncbi.nlm.nih.gov/pubmed/24714620 http://dx.doi.org/10.1371/journal.pone.0094192

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