Cargando…
ZBED6 Modulates the Transcription of Myogenic Genes in Mouse Myoblast Cells
ZBED6 is a recently discovered transcription factor, unique to placental mammals, that has evolved from a domesticated DNA transposon. It acts as a repressor at the IGF2 locus. Here we show that ZBED6 acts as a transcriptional modulator in mouse myoblast cells, where more than 700 genes were differe...
Autores principales: | Jiang, Lin, Wallerman, Ola, Younis, Shady, Rubin, Carl-Johan, Gilbert, Elizabeth R., Sundström, Elisabeth, Ghazal, Awaisa, Zhang, Xiaolan, Wang, Li, Mikkelsen, Tarjei S., Andersson, Göran, Andersson, Leif |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979763/ https://www.ncbi.nlm.nih.gov/pubmed/24714595 http://dx.doi.org/10.1371/journal.pone.0094187 |
Ejemplares similares
-
ZBED Evolution: Repeated Utilization of DNA Transposons as Regulators of Diverse Host Functions
por: Hayward, Alexander, et al.
Publicado: (2013) -
ZBED6 regulates Igf2 expression partially through its regulation of miR483 expression
por: Naboulsi, Rakan, et al.
Publicado: (2021) -
ZBED6, a Novel Transcription Factor Derived from a Domesticated DNA Transposon Regulates IGF2 Expression and Muscle Growth
por: Markljung, Ellen, et al.
Publicado: (2009) -
The ZBED6–IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals
por: Younis, Shady, et al.
Publicado: (2018) -
ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation
por: Wang, Xuan, et al.
Publicado: (2021)