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Role of capecitabine in treating metastatic colorectal cancer in Chinese patients
The China Food and Drug Administration approved the use of capecitabine in patients with metastatic colorectal cancer (mCRC) in 2004. This paper reviews the available information of capecitabine in Chinese patients with mCRC, focusing on its effectiveness and safety against mCRC. Identification of a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979786/ https://www.ncbi.nlm.nih.gov/pubmed/24729715 http://dx.doi.org/10.2147/OTT.S38843 |
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author | Wang, Feng Wang, Feng-Hua Bai, Long Xu, Rui-Hua |
author_facet | Wang, Feng Wang, Feng-Hua Bai, Long Xu, Rui-Hua |
author_sort | Wang, Feng |
collection | PubMed |
description | The China Food and Drug Administration approved the use of capecitabine in patients with metastatic colorectal cancer (mCRC) in 2004. This paper reviews the available information of capecitabine in Chinese patients with mCRC, focusing on its effectiveness and safety against mCRC. Identification of all eligible studies was made by searching the PubMed and Wanfang database from 2000 to 2013. Published data examining various aspects of clinical response and tolerability with capecitabine alone or in combination with other chemotherapeutic or biological agents for first- and second-line mCRC were examined. Capecitabine and its combination displayed high efficacy in Chinese patients with mCRC. Toxicities are generally manageable, and elderly patients can tolerate capecitabine well. |
format | Online Article Text |
id | pubmed-3979786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-39797862014-04-11 Role of capecitabine in treating metastatic colorectal cancer in Chinese patients Wang, Feng Wang, Feng-Hua Bai, Long Xu, Rui-Hua Onco Targets Ther Review The China Food and Drug Administration approved the use of capecitabine in patients with metastatic colorectal cancer (mCRC) in 2004. This paper reviews the available information of capecitabine in Chinese patients with mCRC, focusing on its effectiveness and safety against mCRC. Identification of all eligible studies was made by searching the PubMed and Wanfang database from 2000 to 2013. Published data examining various aspects of clinical response and tolerability with capecitabine alone or in combination with other chemotherapeutic or biological agents for first- and second-line mCRC were examined. Capecitabine and its combination displayed high efficacy in Chinese patients with mCRC. Toxicities are generally manageable, and elderly patients can tolerate capecitabine well. Dove Medical Press 2014-04-02 /pmc/articles/PMC3979786/ /pubmed/24729715 http://dx.doi.org/10.2147/OTT.S38843 Text en © 2014 Wang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Wang, Feng Wang, Feng-Hua Bai, Long Xu, Rui-Hua Role of capecitabine in treating metastatic colorectal cancer in Chinese patients |
title | Role of capecitabine in treating metastatic colorectal cancer in Chinese patients |
title_full | Role of capecitabine in treating metastatic colorectal cancer in Chinese patients |
title_fullStr | Role of capecitabine in treating metastatic colorectal cancer in Chinese patients |
title_full_unstemmed | Role of capecitabine in treating metastatic colorectal cancer in Chinese patients |
title_short | Role of capecitabine in treating metastatic colorectal cancer in Chinese patients |
title_sort | role of capecitabine in treating metastatic colorectal cancer in chinese patients |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979786/ https://www.ncbi.nlm.nih.gov/pubmed/24729715 http://dx.doi.org/10.2147/OTT.S38843 |
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