Impact of Amino Acid Substitutions in Two Functional Domains of Ku80: DNA-Damage-Sensing Ability of Ku80 and Survival after Irradiation

Various chemotherapeutic drugs, such as etoposide, and ionizing radiation (IR) have been clinically applied for the treatment of many types of animal and human malignancies. IR and chemotheraputic drugs kill tumor cells mainly by inducing DNA double-strand breaks (DSBs). On the other hand, unrepaire...

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Detalles Bibliográficos
Autores principales: KOIKE, Manabu, YUTOKU, Yasutomo, KOIKE, Aki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2013
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979949/
https://www.ncbi.nlm.nih.gov/pubmed/24025432
http://dx.doi.org/10.1292/jvms.13-0283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979949/
https://www.ncbi.nlm.nih.gov/pubmed/24025432
http://dx.doi.org/10.1292/jvms.13-0283

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