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Relationship between ABO blood group and Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. ALL affects both children and adults. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal pr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shahid Sadoughi University of Medical Sciences
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980014/ https://www.ncbi.nlm.nih.gov/pubmed/24734156 |
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author | Tavasolian, F Abdollahi, E Vakili, M Amini, A |
author_facet | Tavasolian, F Abdollahi, E Vakili, M Amini, A |
author_sort | Tavasolian, F |
collection | PubMed |
description | Acute lymphoblastic leukemia (ALL) constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. ALL affects both children and adults. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms. The aim of this study was to investigate the association between ALL and ABO blood group. MATERIAL AND METHOD: This is a case-control study that was carried out in Amir Oncology Hospital in Shiraz during 2011 to2013. The case group consisted of 293 patients with acute lymphoblastic leukemia. And compared with 300 subject in control group ( the age in the case group was between 2-5 year, and the age in the control group was between 2-45 year) .Statistical analyzes was done performed by chi –square test. The results was considered significant when p value <0.05. (CI:0.95) RESULTS: The ABO blood group distribution was 82(A), 59 (B), 24 (AB) and 128(O) in patient with Acute Lymphoblastic Leukemia and the blood group of 300 participants in the control group include, 63% (25) A, 69% (25.6) B, 18 % 06.8) AB and 101% (42.6) O. The ABO blood group distribution showed that there is significant differences between ABO blood group and patients with acute lymphoblastic leukemia . CONCLUSION: This study showed significant association between ALL and ABO blood group and showed that blood group AB was associated with a higher risk of All (p value<0.001). |
format | Online Article Text |
id | pubmed-3980014 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Shahid Sadoughi University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-39800142014-04-14 Relationship between ABO blood group and Acute Lymphoblastic Leukemia Tavasolian, F Abdollahi, E Vakili, M Amini, A Iran J Ped Hematol Oncol Original Article Acute lymphoblastic leukemia (ALL) constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. ALL affects both children and adults. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms. The aim of this study was to investigate the association between ALL and ABO blood group. MATERIAL AND METHOD: This is a case-control study that was carried out in Amir Oncology Hospital in Shiraz during 2011 to2013. The case group consisted of 293 patients with acute lymphoblastic leukemia. And compared with 300 subject in control group ( the age in the case group was between 2-5 year, and the age in the control group was between 2-45 year) .Statistical analyzes was done performed by chi –square test. The results was considered significant when p value <0.05. (CI:0.95) RESULTS: The ABO blood group distribution was 82(A), 59 (B), 24 (AB) and 128(O) in patient with Acute Lymphoblastic Leukemia and the blood group of 300 participants in the control group include, 63% (25) A, 69% (25.6) B, 18 % 06.8) AB and 101% (42.6) O. The ABO blood group distribution showed that there is significant differences between ABO blood group and patients with acute lymphoblastic leukemia . CONCLUSION: This study showed significant association between ALL and ABO blood group and showed that blood group AB was associated with a higher risk of All (p value<0.001). Shahid Sadoughi University of Medical Sciences 2014 2014-03-15 /pmc/articles/PMC3980014/ /pubmed/24734156 Text en © 2014 Iranian Journal of Pediatric Hematology Oncology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Tavasolian, F Abdollahi, E Vakili, M Amini, A Relationship between ABO blood group and Acute Lymphoblastic Leukemia |
title | Relationship between ABO blood group and Acute Lymphoblastic Leukemia |
title_full | Relationship between ABO blood group and Acute Lymphoblastic Leukemia |
title_fullStr | Relationship between ABO blood group and Acute Lymphoblastic Leukemia |
title_full_unstemmed | Relationship between ABO blood group and Acute Lymphoblastic Leukemia |
title_short | Relationship between ABO blood group and Acute Lymphoblastic Leukemia |
title_sort | relationship between abo blood group and acute lymphoblastic leukemia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980014/ https://www.ncbi.nlm.nih.gov/pubmed/24734156 |
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