Cargando…

Relationship between ABO blood group and Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. ALL affects both children and adults. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Tavasolian, F, Abdollahi, E, Vakili, M, Amini, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Sadoughi University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980014/
https://www.ncbi.nlm.nih.gov/pubmed/24734156
_version_ 1782310797429440512
author Tavasolian, F
Abdollahi, E
Vakili, M
Amini, A
author_facet Tavasolian, F
Abdollahi, E
Vakili, M
Amini, A
author_sort Tavasolian, F
collection PubMed
description Acute lymphoblastic leukemia (ALL) constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. ALL affects both children and adults. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms. The aim of this study was to investigate the association between ALL and ABO blood group. MATERIAL AND METHOD: This is a case-control study that was carried out in Amir Oncology Hospital in Shiraz during 2011 to2013. The case group consisted of 293 patients with acute lymphoblastic leukemia. And compared with 300 subject in control group ( the age in the case group was between 2-5 year, and the age in the control group was between 2-45 year) .Statistical analyzes was done performed by chi –square test. The results was considered significant when p value <0.05. (CI:0.95) RESULTS: The ABO blood group distribution was 82(A), 59 (B), 24 (AB) and 128(O) in patient with Acute Lymphoblastic Leukemia and the blood group of 300 participants in the control group include, 63% (25) A, 69% (25.6) B, 18 % 06.8) AB and 101% (42.6) O. The ABO blood group distribution showed that there is significant differences between ABO blood group and patients with acute lymphoblastic leukemia . CONCLUSION: This study showed significant association between ALL and ABO blood group and showed that blood group AB was associated with a higher risk of All (p value<0.001).
format Online
Article
Text
id pubmed-3980014
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Shahid Sadoughi University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-39800142014-04-14 Relationship between ABO blood group and Acute Lymphoblastic Leukemia Tavasolian, F Abdollahi, E Vakili, M Amini, A Iran J Ped Hematol Oncol Original Article Acute lymphoblastic leukemia (ALL) constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. ALL affects both children and adults. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms. The aim of this study was to investigate the association between ALL and ABO blood group. MATERIAL AND METHOD: This is a case-control study that was carried out in Amir Oncology Hospital in Shiraz during 2011 to2013. The case group consisted of 293 patients with acute lymphoblastic leukemia. And compared with 300 subject in control group ( the age in the case group was between 2-5 year, and the age in the control group was between 2-45 year) .Statistical analyzes was done performed by chi –square test. The results was considered significant when p value <0.05. (CI:0.95) RESULTS: The ABO blood group distribution was 82(A), 59 (B), 24 (AB) and 128(O) in patient with Acute Lymphoblastic Leukemia and the blood group of 300 participants in the control group include, 63% (25) A, 69% (25.6) B, 18 % 06.8) AB and 101% (42.6) O. The ABO blood group distribution showed that there is significant differences between ABO blood group and patients with acute lymphoblastic leukemia . CONCLUSION: This study showed significant association between ALL and ABO blood group and showed that blood group AB was associated with a higher risk of All (p value<0.001). Shahid Sadoughi University of Medical Sciences 2014 2014-03-15 /pmc/articles/PMC3980014/ /pubmed/24734156 Text en © 2014 Iranian Journal of Pediatric Hematology Oncology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Tavasolian, F
Abdollahi, E
Vakili, M
Amini, A
Relationship between ABO blood group and Acute Lymphoblastic Leukemia
title Relationship between ABO blood group and Acute Lymphoblastic Leukemia
title_full Relationship between ABO blood group and Acute Lymphoblastic Leukemia
title_fullStr Relationship between ABO blood group and Acute Lymphoblastic Leukemia
title_full_unstemmed Relationship between ABO blood group and Acute Lymphoblastic Leukemia
title_short Relationship between ABO blood group and Acute Lymphoblastic Leukemia
title_sort relationship between abo blood group and acute lymphoblastic leukemia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980014/
https://www.ncbi.nlm.nih.gov/pubmed/24734156
work_keys_str_mv AT tavasolianf relationshipbetweenabobloodgroupandacutelymphoblasticleukemia
AT abdollahie relationshipbetweenabobloodgroupandacutelymphoblasticleukemia
AT vakilim relationshipbetweenabobloodgroupandacutelymphoblasticleukemia
AT aminia relationshipbetweenabobloodgroupandacutelymphoblasticleukemia