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A cautionary note on ignoring polygenic background when mapping quantitative trait loci via recombinant congenic strains
In gene mapping, it is common to test for association between the phenotype and the genotype at a large number of loci, i.e., the same response variable is used repeatedly to test a large number of non-independent and non-nested hypotheses. In many of these genetic problems, the underlying model is...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980105/ https://www.ncbi.nlm.nih.gov/pubmed/24765102 http://dx.doi.org/10.3389/fgene.2014.00068 |