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Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations
The distribution of mutational fitness effects (DMFE) is crucial to the evolutionary fate of quasispecies. In this article we analyze the effect of the DMFE on the dynamics of a large quasispecies by means of a phenotypic version of the classic Eigen's model that incorporates beneficial, neutra...
Autores principales: | Sardanyés, Josep, Simó, Carles, Martínez, Regina, Solé, Ricard V., Elena, Santiago F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980229/ https://www.ncbi.nlm.nih.gov/pubmed/24713667 http://dx.doi.org/10.1038/srep04625 |
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