Cargando…

An adaptive biomarker strategy clinical trial design

Detalles Bibliográficos
Autores principales:	Wason, James, Stallard, Nigel, Dunn, Janet, Stein, Rob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Oral Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980297/ http://dx.doi.org/10.1186/1745-6215-14-S1-O103

Ejemplares similares

Adaptive designs for clinical trials assessing biomarker-guided treatment strategies
por: Wason, J, et al.
Publicado: (2014)

An adaptive seamless phase II/III clinical trial design incorporating short-term endpoint information
por: Stallard, Nigel
Publicado: (2011)

Using adaptive designs for decision making within the optima trial: optimal personalized treatment of early breast cancer using multi-parameter tests
por: Dunn, Janet, et al.
Publicado: (2013)

Optimal design for multi-arm multi-stage clinical trials
por: Wason, James MS, et al.
Publicado: (2011)

The use of early decision modelling and value of information analysis in an adaptive trial design: results from the OPTIMA preliminary study
por: Hall, Peter, et al.
Publicado: (2015)

Adaptive enrichment in biomarker-stratified clinical trial design
por: Parashar, Deepak, et al.
Publicado: (2013)

Treatment selection in multi-arm, multi-stage clinical trials
por: Jaki, Thomas, et al.
Publicado: (2013)

Efficient design of a phase III trial of competing tests for personalised cancer treatment in the absence of gold standard outcome data: challenges and potential solutions
por: Hall, Peter, et al.
Publicado: (2013)

An adaptive trial design for updating the threshold of a continuous biomarker
por: Spencer, Amy, et al.
Publicado: (2015)

Designing a preliminary adaptive study to inform a biomarker trial in Psoriasis
por: Prevost, Andrew T, et al.
Publicado: (2011)

A series of decision-theoretic phase II trials of related treatments
por: Hee, Siew Wan, et al.
Publicado: (2013)

Estimation bias in survival data within clinical trials that use adaptive seamless designs
por: Khan, Josephine, et al.
Publicado: (2015)

A multi-stage drop-the-losers design for multi-arm clinical trials
por: Wason, James, et al.
Publicado: (2016)

A comparison of bayesian adaptive randomization and multi-stage designs for multi-arm clinical trials
por: Wason, James, et al.
Publicado: (2013)

Meandering journey towards routine trial adaptation: survey results on barriers to use of adaptive designs in confirmatory trials
por: Dimairo, Munyaradzi, et al.
Publicado: (2015)

Evaluating statistical characteristics of biomarker-guided trial designs
por: Antoniou, Miranta, et al.
Publicado: (2015)

Designing trials of complex interventions for efficacy and mechanisms evaluation
por: Emsley, Richard A, et al.
Publicado: (2011)

Implementation of adaptive dose-finding designs in two early phase haematological trials: clinical, operational, and methodological challenges
por: Yap, Christina, et al.
Publicado: (2013)

Practicalities of using an adaptive design for decision making within the optima trial: optimal personalized treatment of early breast cancer using multi-parameter tests
por: Dunn, Janet, et al.
Publicado: (2015)

Using continuous data on tumour measurements to improve inference in phase II cancer studies
por: Wason, James, et al.
Publicado: (2013)

Testosterone replacement in young male cancer survivors (TRYMS) - pragmatic adaptation of trial design for a trial struggling with recruitment
por: Smith, Isabelle, et al.
Publicado: (2015)

Design, validity and clinical utility of smartphone app to assess short-term pain trajectories
por: Bedson, John, et al.
Publicado: (2015)

Type I error control in biomarker-stratified clinical trials
por: Parashar, Deepak, et al.
Publicado: (2015)

What can available randomised controlled trials evaluating monitoring strategies tell us about the design and analysis of future trials?
por: Dinnes, Jacqueline, et al.
Publicado: (2011)

Translating imaging biomarkers into clinical practice
por: O'Connor, James PB
Publicado: (2015)

Efficient Adaptive Designs for Clinical Trials of Interventions for COVID-19
por: Stallard, Nigel, et al.
Publicado: (2020)

Molecular heterogeneity of breast cancer: implications for treatment and clinical trial design
por: Pusztai, L
Publicado: (2009)

Software tools for implementing simulation studies in adaptive seamless designs: introducing R package ASD
por: Parsons, Nick, et al.
Publicado: (2011)

An alternative method to analyse the biomarker‐strategy design
por: Kunz, Cornelia Ursula, et al.
Publicado: (2018)

Revisiting the multi-armed bandit model for the optimal design of clinical trials: benefits and drawbacks
por: Villar, Sofia S, et al.
Publicado: (2013)

Host response to tuberculosis as basis for rational design of vaccines and biomarkers
por: Kaufmann, Stefan HE
Publicado: (2010)

Using a Bayesian approach with reverse philosophy to design clinical trials in rare diseases
por: Billingham, Lucinda, et al.
Publicado: (2013)

The evolution of and challenges in defining the clinical endpoint in tuberculosis treatment trials with non-inferiority designs
por: Phillips, Patrick PJ, et al.
Publicado: (2011)

The FRAGILOME project, a strategy for the discovery of new gene biomarkers in cancer
por: Schwab, Manfred
Publicado: (2010)

Strategies to reduce attrition in randomised trials
por: Brueton, Valerie, et al.
Publicado: (2011)

Design, conduct and challenges of a clinical trial utilizing elastic light scattering spectroscopy in the thyroid
por: Rosen, Jennifer, et al.
Publicado: (2010)

Considering the design effect for the stepped wedge trial: what can it tell us?
por: Thompson, Jennifer, et al.
Publicado: (2015)

Adaptive dose-finding designs to identify multiple doses that achieve multiple response targets
por: Bond, Simon, et al.
Publicado: (2013)

The value of evidence synthesis in randomised controlled trial (RCT) design, conduct and analysis: MRC clinical trials unit (CTU) at UCL experience
por: Tierney, Jayne F, et al.
Publicado: (2015)

Designing the CORONIS trial. Why a non-regular fractional factorial design?
por: Hardy, Pollyanna, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_jh6cmbofc8vjq8pmq5md7qbs82