Cargando…

A novel adaptive trial design: randomised evaluation of molecular guided therapy for diffuse large b-cell lymphoma with bortezomib (REMODL-B) with two interim analyses to explore safety and efficacy

Detalles Bibliográficos
Autores principales: Maishman, Tom, Stanton, Louise, Davies, Andy, Barrans, Sharon, Worrillow, Lisa, Mamot, Christoph, Care, Matt, Immins, Tikki, Hamid, Debbie, McMillan, Andrew, Fields, Paul, Jack, Andrew, Johnson, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980503/
http://dx.doi.org/10.1186/1745-6215-14-S1-O77
_version_ 1782479539693158400
author Maishman, Tom
Stanton, Louise
Davies, Andy
Barrans, Sharon
Worrillow, Lisa
Mamot, Christoph
Care, Matt
Immins, Tikki
Hamid, Debbie
McMillan, Andrew
Fields, Paul
Jack, Andrew
Johnson, Peter
author_facet Maishman, Tom
Stanton, Louise
Davies, Andy
Barrans, Sharon
Worrillow, Lisa
Mamot, Christoph
Care, Matt
Immins, Tikki
Hamid, Debbie
McMillan, Andrew
Fields, Paul
Jack, Andrew
Johnson, Peter
author_sort Maishman, Tom
collection PubMed
description
format Online
Article
Text
id pubmed-3980503
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-39805032014-04-24 A novel adaptive trial design: randomised evaluation of molecular guided therapy for diffuse large b-cell lymphoma with bortezomib (REMODL-B) with two interim analyses to explore safety and efficacy Maishman, Tom Stanton, Louise Davies, Andy Barrans, Sharon Worrillow, Lisa Mamot, Christoph Care, Matt Immins, Tikki Hamid, Debbie McMillan, Andrew Fields, Paul Jack, Andrew Johnson, Peter Trials Oral Presentation BioMed Central 2013-11-29 /pmc/articles/PMC3980503/ http://dx.doi.org/10.1186/1745-6215-14-S1-O77 Text en Copyright © 2013 Maishman et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Oral Presentation
Maishman, Tom
Stanton, Louise
Davies, Andy
Barrans, Sharon
Worrillow, Lisa
Mamot, Christoph
Care, Matt
Immins, Tikki
Hamid, Debbie
McMillan, Andrew
Fields, Paul
Jack, Andrew
Johnson, Peter
A novel adaptive trial design: randomised evaluation of molecular guided therapy for diffuse large b-cell lymphoma with bortezomib (REMODL-B) with two interim analyses to explore safety and efficacy
title A novel adaptive trial design: randomised evaluation of molecular guided therapy for diffuse large b-cell lymphoma with bortezomib (REMODL-B) with two interim analyses to explore safety and efficacy
title_full A novel adaptive trial design: randomised evaluation of molecular guided therapy for diffuse large b-cell lymphoma with bortezomib (REMODL-B) with two interim analyses to explore safety and efficacy
title_fullStr A novel adaptive trial design: randomised evaluation of molecular guided therapy for diffuse large b-cell lymphoma with bortezomib (REMODL-B) with two interim analyses to explore safety and efficacy
title_full_unstemmed A novel adaptive trial design: randomised evaluation of molecular guided therapy for diffuse large b-cell lymphoma with bortezomib (REMODL-B) with two interim analyses to explore safety and efficacy
title_short A novel adaptive trial design: randomised evaluation of molecular guided therapy for diffuse large b-cell lymphoma with bortezomib (REMODL-B) with two interim analyses to explore safety and efficacy
title_sort novel adaptive trial design: randomised evaluation of molecular guided therapy for diffuse large b-cell lymphoma with bortezomib (remodl-b) with two interim analyses to explore safety and efficacy
topic Oral Presentation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980503/
http://dx.doi.org/10.1186/1745-6215-14-S1-O77
work_keys_str_mv AT maishmantom anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT stantonlouise anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT daviesandy anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT barranssharon anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT worrillowlisa anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT mamotchristoph anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT carematt anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT imminstikki anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT hamiddebbie anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT mcmillanandrew anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT fieldspaul anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT jackandrew anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT johnsonpeter anoveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT maishmantom noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT stantonlouise noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT daviesandy noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT barranssharon noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT worrillowlisa noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT mamotchristoph noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT carematt noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT imminstikki noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT hamiddebbie noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT mcmillanandrew noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT fieldspaul noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT jackandrew noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy
AT johnsonpeter noveladaptivetrialdesignrandomisedevaluationofmolecularguidedtherapyfordiffuselargebcelllymphomawithbortezomibremodlbwithtwointerimanalysestoexploresafetyandefficacy