Cargando…

Clinical trials in rare diseases: a review of practice

Detalles Bibliográficos
Autores principales:	Bell, Stuart, Williamson, Paula, Day, Simon, Wheatley, Keith, Whitehead, John, Smith, Catrin Tudur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980535/ http://dx.doi.org/10.1186/1745-6215-14-S1-P34

Ejemplares similares

The trials and tribulations of accessing data from routine sources
por: Powell, Graham, et al.
Publicado: (2015)

A comparison of interventional clinical trials in rare versus non-rare diseases: an analysis of ClinicalTrials.gov
por: Bell, Stuart A, et al.
Publicado: (2014)

The use of historical priors to improve the efficiency of phase II clinical trials with time-to-event endpoints
por: Jackson, Richard, et al.
Publicado: (2013)

Simulation study - handling missing covariates in the context of external validation
por: Bonnett, Laura J, et al.
Publicado: (2011)

Good practice principles for sharing individual participant data from publicly funded clinical trials
por: Smith, Catrin Tudur, et al.
Publicado: (2015)

The consensus studysquamous cell carcinoma of the oropharynx: late phase clinical trials; core outcomes
por: Waters, Aoife, et al.
Publicado: (2013)

Feasibility of establishing a central repository for the individual participant data from research studies
por: Smith, Catrin Tudur, et al.
Publicado: (2011)

The paediatric hepatic international tumour trial (PHITT): clinical trial design in rare disease
por: Moroz, Veronica, et al.
Publicado: (2015)

The CONSENSUS Study: Preliminary results of a mixed methods study to develop a core outcome set for late phase clinical trials in Oropharyngeal Cancer
por: Waters, Aoife M I, et al.
Publicado: (2015)

Flexible trial design in a rare condition
por: Moroz, Veronica, et al.
Publicado: (2013)

Individual participant data meta-analyses compared with meta-analyses based on aggregate data
por: Smith, Catrin Tudur, et al.
Publicado: (2011)

Elicitation of expert prior opinion: application to the mypan trial in childhood polyarteritis nodosa
por: Hampson, Lisa, et al.
Publicado: (2014)

Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit
por: Tudur Smith, Catrin, et al.
Publicado: (2014)

A review of recruitment of children to randomised clinical trials in the NIHR clinical research network portfolio
por: Kaur, Geetinder, et al.
Publicado: (2013)

Interventions to improve recruitment and retention in clinical trials: a survey and workshop to assess current practice and future priorities
por: Bower, Peter, et al.
Publicado: (2014)

External validation of a prognostic index
por: Bonnett, Laura, et al.
Publicado: (2013)

Anti-epileptic drug harms: issues for meta-analysis
por: Smith, Catrin Tudur, et al.
Publicado: (2011)

A mapping and gapping analysis of patient and public involvement in a clinical trials unit
por: Bagley, Heather, et al.
Publicado: (2013)

Adjusting for informative missing outcome data in clinical trials with longitudinal study designs
por: Kolamunnage-Dona, Ruwanthi, et al.
Publicado: (2013)

Development of an online resource for recruitment research in clinical trials (ORRCA)
por: Harman, Nicola, et al.
Publicado: (2015)

“To have, to hold, from this day forward”: understanding current practice regarding the retention of trial participants
por: Daykin, Anne, et al.
Publicado: (2015)

The trials methodological research agenda: results from a priority setting exercise
por: Tudur Smith, Catrin, et al.
Publicado: (2014)

The use of systematic reviews in the design of randomised trials
por: Jones, Ashley P, et al.
Publicado: (2011)

Barriers to recruitment for surgical trials in head and neck oncology: a survey of trial investigators
por: Kaur, Geetinder, et al.
Publicado: (2013)

Does the low prevalence affect the sample size of interventional clinical trials of rare diseases? An analysis of data from the aggregate analysis of clinicaltrials.gov
por: Hee, Siew Wan, et al.
Publicado: (2017)

Indirect Comparisons: A Review of Reporting and Methodological Quality
por: Donegan, Sarah, et al.
Publicado: (2010)

Sharing Individual Participant Data from Clinical Trials: An Opinion Survey Regarding the Establishment of a Central Repository
por: Tudur Smith, Catrin, et al.
Publicado: (2014)

Multiple treatment comparisons in epilepsy monotherapy trials
por: Tudur Smith, Catrin, et al.
Publicado: (2007)

TRYMS: the ethical and practical considerations of a double-blind placebo controlled randomised clinical trial
por: Swain, Jayne, et al.
Publicado: (2015)

Using systematic reviews to identify research gaps - a case study: mIBG for the treatment of neuroblastoma in children
por: Wilson, Jayne, et al.
Publicado: (2013)

UK publicly funded Clinical Trials Units supported a controlled access approach to share individual participant data but highlighted concerns
por: Hopkins, Carolyn, et al.
Publicado: (2016)

Clinical development of nitisinone for alkaptonuria (developakure) - a rare disease clinical trials design
por: Psarelli, Eftychia Eirini, et al.
Publicado: (2013)

Do pilot trials reliably predict recruitment and retention rates for full trial? A review of HTA funded trials
por: Whitehead, Amy, et al.
Publicado: (2015)

EU Clinical trial regulation in the environment of rare diseases: time for a change
por: Zimmermann, Martine
Publicado: (2010)

‘Getting back to normal’: using patients’ lived experience to inform a core outcome set for cardiac arrest clinical trials
por: Whitehead, Laura, et al.
Publicado: (2015)

A review of the description of patient withdrawal in trial protocols and patient information sheets (PIS)
por: Kearney, Anna, et al.
Publicado: (2015)

Are patients and health care professionals influenced by each other's’ opinions about the outcomes to measure in localised prostate cancer effectiveness trials?
por: MacLennan, Steven, et al.
Publicado: (2015)

Public health approach of clinical trials: Cuban’s experience of research translation into clinical practice
por: Pascual, Maria A, et al.
Publicado: (2014)

Does ‘mapping’ the evidence usefully inform the research question prioritisation process in systematic reviews?
por: Main, Caroline, et al.
Publicado: (2015)

Resource implications of preparing individual participant data from a clinical trial to share with external researchers
por: Tudur Smith, Catrin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8k0rq5755jcosnff3pbde63rjo