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Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature

Osteoblastoma (OB) is a rare bony neoplasm constituting around 1% of all primary bone tumors. Although the vertebrae and long bones are the most common sites affected by OB, skull remains a relatively uncommon site of occurrence. Aggressive variant of OB is histologically intermediate between an ind...

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Autores principales: Singh, Devesh Kumar, Das, Kuntal Kanti, Mehrotra, Anant, Srivastava, Arun Kumar, Jaiswal, Awadhesh Kumar, Gupta, Pallav, Behari, Sanjay, Kumar, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980559/
https://www.ncbi.nlm.nih.gov/pubmed/24744565
http://dx.doi.org/10.4103/0974-8237.128533
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author Singh, Devesh Kumar
Das, Kuntal Kanti
Mehrotra, Anant
Srivastava, Arun Kumar
Jaiswal, Awadhesh Kumar
Gupta, Pallav
Behari, Sanjay
Kumar, Raj
author_facet Singh, Devesh Kumar
Das, Kuntal Kanti
Mehrotra, Anant
Srivastava, Arun Kumar
Jaiswal, Awadhesh Kumar
Gupta, Pallav
Behari, Sanjay
Kumar, Raj
author_sort Singh, Devesh Kumar
collection PubMed
description Osteoblastoma (OB) is a rare bony neoplasm constituting around 1% of all primary bone tumors. Although the vertebrae and long bones are the most common sites affected by OB, skull remains a relatively uncommon site of occurrence. Aggressive variant of OB is histologically intermediate between an indolent conventional OB and a malignant osteosarcoma. To the best of our knowledge, aggressive osteoblastoma (AO) affecting the craniovertebral junction has not been previously described in the literature. In this report, we present a 34-year-old gentleman who presented with a mass involving the left side of the neck and oral cavity along with ipsilateral lower cranial nerve paresis. Computed tomography and magnetic resonance imaging scans of the craniovertebral junction revealed a heterogeneously enhancing expansile lesion with areas of destruction involving the clivus, left sided jugular foramen and left side of first two cervical vertebras. Angiography showed distortion of the V3 segment of the left vertebral artery and shift of the ipsilateral internal carotid artery. The tumor was maximally excised through far lateral approach. Histopathologic examination revealed a diagnosis of AO. The patient was referred for radiotherapy for the residual tumor and was doing well at 5 months follow-up.
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spelling pubmed-39805592014-04-17 Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature Singh, Devesh Kumar Das, Kuntal Kanti Mehrotra, Anant Srivastava, Arun Kumar Jaiswal, Awadhesh Kumar Gupta, Pallav Behari, Sanjay Kumar, Raj J Craniovertebr Junction Spine Case Report Osteoblastoma (OB) is a rare bony neoplasm constituting around 1% of all primary bone tumors. Although the vertebrae and long bones are the most common sites affected by OB, skull remains a relatively uncommon site of occurrence. Aggressive variant of OB is histologically intermediate between an indolent conventional OB and a malignant osteosarcoma. To the best of our knowledge, aggressive osteoblastoma (AO) affecting the craniovertebral junction has not been previously described in the literature. In this report, we present a 34-year-old gentleman who presented with a mass involving the left side of the neck and oral cavity along with ipsilateral lower cranial nerve paresis. Computed tomography and magnetic resonance imaging scans of the craniovertebral junction revealed a heterogeneously enhancing expansile lesion with areas of destruction involving the clivus, left sided jugular foramen and left side of first two cervical vertebras. Angiography showed distortion of the V3 segment of the left vertebral artery and shift of the ipsilateral internal carotid artery. The tumor was maximally excised through far lateral approach. Histopathologic examination revealed a diagnosis of AO. The patient was referred for radiotherapy for the residual tumor and was doing well at 5 months follow-up. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3980559/ /pubmed/24744565 http://dx.doi.org/10.4103/0974-8237.128533 Text en Copyright: © Journal of Craniovertebral Junction and Spine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Singh, Devesh Kumar
Das, Kuntal Kanti
Mehrotra, Anant
Srivastava, Arun Kumar
Jaiswal, Awadhesh Kumar
Gupta, Pallav
Behari, Sanjay
Kumar, Raj
Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature
title Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature
title_full Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature
title_fullStr Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature
title_full_unstemmed Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature
title_short Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature
title_sort aggressive osteoblastoma involving the craniovertebral junction: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980559/
https://www.ncbi.nlm.nih.gov/pubmed/24744565
http://dx.doi.org/10.4103/0974-8237.128533
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