RPA Antagonizes Microhomology-Mediated Repair of DNA Double-Strand Breaks

Microhomology-mediated end joining (MMEJ) is a Ku and Ligase IV independent mechanism for repair of DNA double-strand breaks, which contributes to chromosome rearrangements. Here we used a chromosomal end-joining assay to determine the genetic requirements for MMEJ in Saccharomyces cerevisiae. We fo...

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Detalles Bibliográficos
Autores principales: Deng, Sarah K, Gibb, Bryan, de Almeida, Mariana Justino, Greene, Eric C, Symington, Lorraine S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980576/
https://www.ncbi.nlm.nih.gov/pubmed/24608368
http://dx.doi.org/10.1038/nsmb.2786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980576/
https://www.ncbi.nlm.nih.gov/pubmed/24608368
http://dx.doi.org/10.1038/nsmb.2786

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