Cargando…

Molecular Perspectives for mu/delta Opioid Receptor Heteromers as Distinct, Functional Receptors

Opioid receptors are the sites of action for morphine and the other opioid drugs. Abundant evidence now demonstrates that different opioid receptor types can physically associate to form heteromers. Understandings of the nature, behavior, and role of these opioid receptor heteromers are developing....

Descripción completa

Detalles Bibliográficos
Autores principales:	Ong, Edmund W., Cahill, Catherine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980742/ https://www.ncbi.nlm.nih.gov/pubmed/24709907 http://dx.doi.org/10.3390/cells3010152

Ejemplares similares

Activation of the Mu-Delta Opioid Receptor Heteromers Blocks Morphine Rewarding Effects
por: Requana Aradas, Ariadna, et al.
Publicado: (2023)

Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers
por: Fujita, Wakako, et al.
Publicado: (2014)

Anti-Analgesic Effect of the Mu/Delta Opioid Receptor Heteromer Revealed by Ligand-Biased Antagonism
por: Milan-Lobo, Laura, et al.
Publicado: (2013)

An Emerging Role for the Delta Opioid Receptor in the Regulation of Mu Opioid Receptor Function
por: Rozenfeld, Raphael, et al.
Publicado: (2007)

Nitro-benzylideneoxymorphone, a bifunctional mu and delta opioid receptor ligand with high mu opioid receptor efficacy
por: Olson, Keith M., et al.
Publicado: (2023)

Receptor and Channel Heteromers as Pain Targets
por: Berg, Kelly A., et al.
Publicado: (2012)

Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits
por: Wang, Dong, et al.
Publicado: (2018)

Adenosine Receptor Heteromers and their Integrative Role in Striatal Function
por: Ferré, Sergi, et al.
Publicado: (2007)

New Insights on Expression and Function of Mu and Delta Opioid Receptors in Mouse Gastrointestinal Tract
por: Feng, Bin
Publicado: (2020)

Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons
por: He, Xinyi Jenny, et al.
Publicado: (2021)

Role of Mu and Delta Opioid Receptors in the Nucleus Accumbens in Cocaine-Seeking Behavior
por: Simmons, Diana, et al.
Publicado: (2009)

Neuroprotection afforded by targeting G protein-coupled receptors in heteromers and by heteromer-selective drugs
por: Franco, Rafael, et al.
Publicado: (2023)

Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon
por: DiCello, Jesse J., et al.
Publicado: (2019)

Kappa but not delta or mu opioid receptors form homodimers at low membrane densities
por: Cechova, Kristina, et al.
Publicado: (2021)

Behavioural and morphological evidence for the involvement of glial cell activation in delta opioid receptor function: implications for the development of opioid tolerance
por: Holdridge, Sarah V, et al.
Publicado: (2007)

On the existence and function of galanin receptor heteromers in the central nervous system
por: Fuxe, Kjell, et al.
Publicado: (2012)

Understanding the Added Value of G-Protein-Coupled Receptor Heteromers
por: Franco, Nuria, et al.
Publicado: (2014)

Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase
por: Navarro, Gemma, et al.
Publicado: (2018)

Molecular signatures of mu opioid receptor and somatostatin receptor 2 in pancreatic cancer
por: Jorand, Raphael, et al.
Publicado: (2016)

Mu and Delta Opioid Receptors Oppositely Regulate Motor Impulsivity in the Signaled Nose Poke Task
por: Olmstead, Mary C., et al.
Publicado: (2009)

Heteromerization of Endogenous Mu and Delta Opioid Receptors Induces Ligand-Selective Co-Targeting to Lysosomes
por: Derouiche, Lyes, et al.
Publicado: (2020)

Distribution of delta and mu opioid receptor mRNA in rodent dorsal root ganglia neurons
por: Quirion, Béatrice, et al.
Publicado: (2022)

Does the kappa opioid receptor system contribute to pain aversion?
por: Cahill, Catherine M., et al.
Publicado: (2014)

Discovery of the First Small-Molecule Opioid Pan Antagonist with Nanomolar Affinity at Mu, Delta, Kappa, and Nociceptin Opioid Receptors
por: Zaveri, Nurulain T., et al.
Publicado: (2015)

A Structure-Activity Relationship Comparison of Imidazodiazepines Binding at Kappa, Mu, and Delta Opioid Receptors and the GABA(A) Receptor
por: Li, Guanguan, et al.
Publicado: (2020)

Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D(2) Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor
por: Vasudevan, Lakshmi, et al.
Publicado: (2019)

Mu-opioid receptor and delta-opioid receptor differentially regulate microglial inflammatory response to control proopiomelanocortin neuronal apoptosis in the hypothalamus: effects of neonatal alcohol
por: Shrivastava, Pallavi, et al.
Publicado: (2017)

A mu–delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks
por: Erbs, Eric, et al.
Publicado: (2014)

Delta Opioid Receptor and Its Peptide: A Receptor-Ligand Neuroprotection
por: Staples, Meaghan, et al.
Publicado: (2013)

Activation of Mu or Delta Opioid Receptors in the Lumbosacral Spinal Cord Is Essential for Ejaculatory Reflexes in Male Rats
por: Kozyrev, Natalie, et al.
Publicado: (2015)

CB1 Agonism Alters Addiction-Related Behaviors in Mice Lacking Mu or Delta Opioid Receptors
por: Roeckel, Laurie-Anne, et al.
Publicado: (2018)

Probing ligand recognition of the opioid pan antagonist AT-076 at nociceptin, kappa, mu, and delta opioid receptors through structure-activity relationships
por: Journigan, V. Blair, et al.
Publicado: (2017)

Receptor-Heteromer Investigation Technology and its application using BRET
por: Johnstone, Elizabeth K. M., et al.
Publicado: (2012)

Investigation of Receptor Heteromers Using NanoBRET Ligand Binding
por: Johnstone, Elizabeth K. M., et al.
Publicado: (2021)

Heteromerization Modulates mu Opioid Receptor Functional Properties in vivo
por: Ugur, Muzeyyen, et al.
Publicado: (2018)

Functional selectivity of EM-2 analogs at the mu-opioid receptor
por: Piekielna-Ciesielska, Justyna, et al.
Publicado: (2023)

Alternative Pre-mRNA Splicing of the Mu Opioid Receptor Gene, OPRM1: Insight into Complex Mu Opioid Actions
por: Liu, Shan, et al.
Publicado: (2021)

Recent Molecular Insights into Agonist-specific Binding to the Mu-Opioid Receptor
por: Zádor, Ferenc, et al.
Publicado: (2022)

Mu Opioid Receptor Actions in the Lateral Habenula
por: Margolis, Elyssa B., et al.
Publicado: (2016)

Interaction between Mu and Delta Opioid Receptor Agonists in an Assay of Capsaicin-Induced Thermal Allodynia in Rhesus Monkeys
por: Negus, S. Stevens, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_3f316ktv8ouoks8ra074snslj0