Development of a Novel BAFF Responsive Cell Line Suitable for Detecting Bioactive BAFF and Neutralizing Antibodies against BAFF-Pathway Inhibiting Therapeutics

BAFF has a critical role in B-cell survival, maturation and function, which makes its pathway a prime therapeutic target for various autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis and Sjögren’s syndrome. A cell-based assay that measures the functional activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Jenny, Yu, Yanbin, Han, Hong, Civoli, Francesca, Zhuang, Yao, Thomas, John, Swanson, Steve, Jing, Shuqian, Gupta, Shalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980743/
https://www.ncbi.nlm.nih.gov/pubmed/24709903
http://dx.doi.org/10.3390/cells3010079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980743/
https://www.ncbi.nlm.nih.gov/pubmed/24709903
http://dx.doi.org/10.3390/cells3010079

Ejemplares similares