Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis

The histone deacetylases HDAC1 and HDAC2 remove acetyl moieties from lysine residues of histones and other proteins and are important regulators of gene expression. By deleting different combinations of Hdac1 and Hdac2 alleles in the epidermis, we reveal a dosage-dependent effect of HDAC1/HDAC2 acti...

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Detalles Bibliográficos
Autores principales: Winter, Mircea, Moser, Mirjam A, Meunier, Dominique, Fischer, Carina, Machat, Georg, Mattes, Katharina, Lichtenberger, Beate M, Brunmeir, Reinhard, Weissmann, Simon, Murko, Christina, Humer, Christina, Meischel, Tina, Brosch, Gerald, Matthias, Patrick, Sibilia, Maria, Seiser, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981143/
https://www.ncbi.nlm.nih.gov/pubmed/24240174
http://dx.doi.org/10.1038/emboj.2013.243

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