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Phaeochromocytoma in a 20-year-old Nigerian, resolving the dilemma of benignity or malignancy

Pheochromocytomas are rare tumors that present a diagnostic challenge in developing countries. They occur in the adrenal gland and as paragangliomas along the sympathetic chain. Clinical features are usually those of sustained or paroxysmal hypertension and complications thereof. Surgical extirpatio...

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Autores principales: Ugwumba, Fred O., Okafor, Okechukwu C., Okoh, Agharighom David, Ajuzieogu, Obinna Virginus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981342/
https://www.ncbi.nlm.nih.gov/pubmed/24765414
http://dx.doi.org/10.4081/cp.2012.e15
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author Ugwumba, Fred O.
Okafor, Okechukwu C.
Okoh, Agharighom David
Ajuzieogu, Obinna Virginus
author_facet Ugwumba, Fred O.
Okafor, Okechukwu C.
Okoh, Agharighom David
Ajuzieogu, Obinna Virginus
author_sort Ugwumba, Fred O.
collection PubMed
description Pheochromocytomas are rare tumors that present a diagnostic challenge in developing countries. They occur in the adrenal gland and as paragangliomas along the sympathetic chain. Clinical features are usually those of sustained or paroxysmal hypertension and complications thereof. Surgical extirpation remains the mainstay of treatment and is greatly facilitated by accurate pre-operative tumor localization. Pre-operative medical management with antihypertensive medication has led to significant reductions in peri-operative mortality. Determination of malignancy is difficult in the absence of obvious metastases. We present a case of left adrenal phechromocytoma that was stabilized. Adrenalectomy had a good outcome and the patient has so far been followed up for a year.
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spelling pubmed-39813422014-04-24 Phaeochromocytoma in a 20-year-old Nigerian, resolving the dilemma of benignity or malignancy Ugwumba, Fred O. Okafor, Okechukwu C. Okoh, Agharighom David Ajuzieogu, Obinna Virginus Clin Pract Case Report Pheochromocytomas are rare tumors that present a diagnostic challenge in developing countries. They occur in the adrenal gland and as paragangliomas along the sympathetic chain. Clinical features are usually those of sustained or paroxysmal hypertension and complications thereof. Surgical extirpation remains the mainstay of treatment and is greatly facilitated by accurate pre-operative tumor localization. Pre-operative medical management with antihypertensive medication has led to significant reductions in peri-operative mortality. Determination of malignancy is difficult in the absence of obvious metastases. We present a case of left adrenal phechromocytoma that was stabilized. Adrenalectomy had a good outcome and the patient has so far been followed up for a year. PAGEPress Publications 2012-01-18 /pmc/articles/PMC3981342/ /pubmed/24765414 http://dx.doi.org/10.4081/cp.2012.e15 Text en ©Copyright F.O. Ugwumba et al., 2012 This work is licensed under a Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0). Licensee PAGEPress, Italy
spellingShingle Case Report
Ugwumba, Fred O.
Okafor, Okechukwu C.
Okoh, Agharighom David
Ajuzieogu, Obinna Virginus
Phaeochromocytoma in a 20-year-old Nigerian, resolving the dilemma of benignity or malignancy
title Phaeochromocytoma in a 20-year-old Nigerian, resolving the dilemma of benignity or malignancy
title_full Phaeochromocytoma in a 20-year-old Nigerian, resolving the dilemma of benignity or malignancy
title_fullStr Phaeochromocytoma in a 20-year-old Nigerian, resolving the dilemma of benignity or malignancy
title_full_unstemmed Phaeochromocytoma in a 20-year-old Nigerian, resolving the dilemma of benignity or malignancy
title_short Phaeochromocytoma in a 20-year-old Nigerian, resolving the dilemma of benignity or malignancy
title_sort phaeochromocytoma in a 20-year-old nigerian, resolving the dilemma of benignity or malignancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981342/
https://www.ncbi.nlm.nih.gov/pubmed/24765414
http://dx.doi.org/10.4081/cp.2012.e15
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