Protective Effect of Cytosolic Phospholipase A2 Inhibition against Inflammation and Degeneration by Promoting Regulatory T Cells in Rats with Experimental Autoimmune Encephalomyelitis

Cytosolic phospholipase A2 (cPLA(2)) is the rate-limiting enzyme that initiates the production of various inflammatory mediators. Previous studies have shown that inhibiting cPLA(2) exerts a neuroprotective effect on experimental autoimmune encephalomyelitis (EAE) by ameliorating the severity of the...

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Detalles Bibliográficos
Autores principales: Yang, Dan, Ji, Hong-Fei, Zhang, Xue-Mei, Yue, Hui, Lin, Lin, Ma, Yu-Yan, Huang, Xiang-nan, Fu, Jin, Wang, Wei-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981565/
https://www.ncbi.nlm.nih.gov/pubmed/24782598
http://dx.doi.org/10.1155/2014/890139

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