Cargando…

Technology transfer and scale down model development strategy for biotherapeutics produced in mammalian cells

Detalles Bibliográficos
Autores principales:	Kochanowski, Nadine, Malphettes, Laetitia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981586/ http://dx.doi.org/10.1186/1753-6561-7-S6-P86

Ejemplares similares

ambr™ Mini-bioreactor as a high-throughput tool for culture process development to accelerate transfer to stainless steel manufacturing scale: comparability study from process performance to product quality attributes
por: Delouvroy, Frédéric, et al.
Publicado: (2015)

Evaluation of the advanced micro-scale bioreactor (ambr™) as a highthroughput tool for cell culture process development
por: Delouvroy, Frédéric, et al.
Publicado: (2013)

Host cell protein platform assay development for therapeutic mAb bioprocessing using mammalian cells
por: Kochanowski, Nadine, et al.
Publicado: (2015)

Scale-up considerations for monoclonal antibody production process: an oxygen transfer flux approach
por: Gimenez, Laura, et al.
Publicado: (2013)

Process development and optimization of fed-batch production processes for therapeutic proteins by CHO cells
por: Clincke, Marie-Françoise, et al.
Publicado: (2013)

Medium and feed optimization for fed-batch production of a monoclonal antibody in CHO cells
por: Kochanowski, Nadine, et al.
Publicado: (2011)

Development and fine-tuning of a scale down model for process characterization studies of a monoclonal antibody upstream production process
por: Harmsen, Mareike, et al.
Publicado: (2011)

Overcoming the clarification challenges of high cell density culture
por: Gimenez, Laura, et al.
Publicado: (2015)

Feeding strategy optimization in interaction with target seeding density of a fed-batch process for monoclonal antibody production
por: Clincke, Marie-Françoise, et al.
Publicado: (2013)

From Clone Selection to 80L Bioreactor Production: Better, Faster, Leaner
por: Clincke, Marie-Françoise, et al.
Publicado: (2015)

Macroscopic modeling of mammalian cell growth and metabolism
por: Ben Yahia, Bassem, et al.
Publicado: (2015)

Antibody disulfide bond reduction during process development: Insights using a scale-down model process
por: Ruaudel, Julie, et al.
Publicado: (2015)

Odor segmentation and identification in an abstract large-scale model of the mammalian olfactory system
por: Benjaminsson, Simon, et al.
Publicado: (2011)

Scaling of spike-timing based neuron model for mammalian olfaction with network size
por: Chen, Bolun, et al.
Publicado: (2014)

Advances in the Development of Biotherapeutics
por: Oliveira, Pedro H., et al.
Publicado: (2015)

Recent developments in scaling down and using single use probes for measuring the live cell concentration by dielectric spectroscopy
por: Carvell, John, et al.
Publicado: (2015)

Engineering characterisation of single-use bioreactor technology for mammalian cell culture applications
por: Odeleye, Akinlolu, et al.
Publicado: (2013)

A large-scale model of the three first stages of the mammalian olfactory system implemented with spiking neurons
por: Kaplan, Bernhard, et al.
Publicado: (2011)

The Development Pathway for Biosimilar Biotherapeutics
por: Zarbin, Marco
Publicado: (2020)

Exploiting Prophage-Mediated Lysis for Biotherapeutic Release by Lactobacillus reuteri
por: Alexander, Laura M., et al.
Publicado: (2019)

Gut microbiota: next frontier in understanding human health and development of biotherapeutics
por: Prakash, Satya, et al.
Publicado: (2011)

A role for central carbon metabolism in mammalian embryonic development?
por: Snaebjornsson, Marteinn, et al.
Publicado: (2014)

Application of a genome-scale model in tandem with enzyme assays for identification of metabolic signatures of high and low CHO cell producers
por: Calmels, Cyrielle, et al.
Publicado: (2019)

Molecular Interaction Characterization Strategies for the Development of New Biotherapeutic Antibody Modalities
por: Wang, Xiangdan, et al.
Publicado: (2020)

Strategies in developing dimethyl sulfoxide (DMSO)-free cryopreservation protocols for biotherapeutics
por: Ekpo, Marlene Davis, et al.
Publicado: (2022)

Strategies for reducing regulatory barriers to focused ultrasound technology
por: Dobrenz, Liz
Publicado: (2015)

Technology toolbox for cell line development - next generation cell line development technologies
por: Laux, Holger, et al.
Publicado: (2015)

Model-based strategy for cell culture seed train layout verified at lab scale
por: Kern, Simon, et al.
Publicado: (2015)

Retinitis Pigmentosa: Progress in Molecular Pathology and Biotherapeutical Strategies
por: Liu, Wanqin, et al.
Publicado: (2022)

Computational modeling of the external tufted cell of the mammalian olfactory bulb
por: Sherwood, William Erik, et al.
Publicado: (2010)

IL-17-producing (©)™T cells are important for the development of arthritis in a rheumatoid arthritis model
por: Akitsu, Aoi, et al.
Publicado: (2012)

Digital on the road down-under
por: Galloway, L, et al.
Publicado: (2006)

Direct evidence for close proximity of catalytic and regulatory domains of heterodimeric sGC based on fluorescence resonance energy transfer
por: Haase, Tobias, et al.
Publicado: (2009)

Integrated BioTherapeutics
por: Aman, M. Javad
Publicado: (2018)

Clinical and radiological features of down's arthropathy
por: Foley, Charlene, et al.
Publicado: (2014)

Cardiac surgical aspects of Down syndrome
por: Mokryk, I, et al.
Publicado: (2013)

Development of the Disturbed Eating Characteristics Scales (DECS)
por: Woodward, Kim, et al.
Publicado: (2014)

Parabacteroides distasonis Properties Linked to the Selection of New Biotherapeutics
por: Chamarande, Jordan, et al.
Publicado: (2022)

Dynamical evolution of spatiotemporal patterns in mammalian middle cortex
por: Schiff, Steven J, et al.
Publicado: (2007)

Metabolic modeling predicts perturbations extending lifespan in yeast and counteracting aging in mammalian muscle
por: Yizhak, Keren, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_0nu1ilav1807d0t13jobfrgu7k