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Osteopontin Is Induced by TGF-β2 and Regulates Metabolic Cell Activity in Cultured Human Optic Nerve Head Astrocytes
The aqueous humor (AH) component transforming growth factor (TGF)-β2 is strongly correlated to primary open-angle glaucoma (POAG), and was shown to up-regulate glaucoma-associated extracellular matrix (ECM) components, members of the ECM degradation system and heat shock proteins (HSP) in primary oc...
Autores principales: | Neumann, Carolin, Garreis, Fabian, Paulsen, Friedrich, Hammer, Christian M., Birke, Marco T., Scholz, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981660/ https://www.ncbi.nlm.nih.gov/pubmed/24718314 http://dx.doi.org/10.1371/journal.pone.0092762 |
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