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Interaction of 6 Mercaptopurine with Calf Thymus DNA – Deciphering the Binding Mode and Photoinduced DNA Damage

DNA is one of the major intracellular targets for a wide range of anticancer and antibiotic drugs. Elucidating the binding between small molecules and DNA provides great help in understanding drug-DNA interactions and in designing of new and promising drugs for clinical use. The ability of small mol...

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Detalles Bibliográficos
Autores principales: Rehman, Sayeed Ur, Yaseen, Zahid, Husain, Mohammed Amir, Sarwar, Tarique, Ishqi, Hassan Mubarak, Tabish, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981731/
https://www.ncbi.nlm.nih.gov/pubmed/24718609
http://dx.doi.org/10.1371/journal.pone.0093913