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Automated Quantification Reveals Hyperglycemia Inhibits Endothelial Angiogenic Function

OBJECTIVE: Diabetes Mellitus (DM) has reached epidemic levels globally. A contributing factor to the development of DM is high blood glucose (hyperglycemia). One complication associated with DM is a decreased angiogenesis. The Matrigel tube formation assay (TFA) is the most widely utilized in vitro...

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Detalles Bibliográficos
Autores principales: Prisco, Anthony R., Bukowy, John D., Hoffmann, Brian R., Karcher, Jamie R., Exner, Eric C., Greene, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981811/
https://www.ncbi.nlm.nih.gov/pubmed/24718615
http://dx.doi.org/10.1371/journal.pone.0094599