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Automated Quantification Reveals Hyperglycemia Inhibits Endothelial Angiogenic Function
OBJECTIVE: Diabetes Mellitus (DM) has reached epidemic levels globally. A contributing factor to the development of DM is high blood glucose (hyperglycemia). One complication associated with DM is a decreased angiogenesis. The Matrigel tube formation assay (TFA) is the most widely utilized in vitro...
Autores principales: | Prisco, Anthony R., Bukowy, John D., Hoffmann, Brian R., Karcher, Jamie R., Exner, Eric C., Greene, Andrew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981811/ https://www.ncbi.nlm.nih.gov/pubmed/24718615 http://dx.doi.org/10.1371/journal.pone.0094599 |
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