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Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria

AMP-kinase (AMPK) activation reduces cardiac hypertrophy, although underlying molecular mechanisms remain unclear. In this study, we elucidated the anti-hypertrophic action of metformin, specifically, the role of the AMPK/eNOS/p53 pathway. H9c2 rat cardiomyocytes were treated with angiotensin II (An...

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Detalles Bibliográficos
Autores principales:	Hernández, Jessica Soto, Barreto-Torres, Giselle, Kuznetsov, Andrey V, Khuchua, Zaza, Javadov, Sabzali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981893/ https://www.ncbi.nlm.nih.gov/pubmed/24444314 http://dx.doi.org/10.1111/jcmm.12220

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