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Netrin-1 promotes adipose tissue macrophage accumulation and insulin resistance in obesity
During obesity, macrophage accumulation in adipose tissue propagates the chronic inflammation and insulin resistance associated with type 2 diabetes. The factors that regulate the accrual of macrophages in adipose are not well understood. Here we show that the neuroimmune guidance cue netrin-1 is hi...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981930/ https://www.ncbi.nlm.nih.gov/pubmed/24584118 http://dx.doi.org/10.1038/nm.3467 |