Induction of ischemic stroke in awake freely moving mice reveals that isoflurane anesthesia can mask the benefits of a neuroprotection therapy

Anesthetics such as isoflurane are commonly used to sedate experimental animals during the induction of stroke. Since these agents are known to modulate synaptic excitability, inflammation and blood flow, they could hinder the development and discovery of new neuroprotection therapies. To address th...

Descripción completa

Detalles Bibliográficos
Autores principales: Seto, Angela, Taylor, Stephanie, Trudeau, Dustin, Swan, Ian, Leung, Jay, Reeson, Patrick, Delaney, Kerry R., Brown, Craig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982055/
https://www.ncbi.nlm.nih.gov/pubmed/24765075
http://dx.doi.org/10.3389/fnene.2014.00001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982055/
https://www.ncbi.nlm.nih.gov/pubmed/24765075
http://dx.doi.org/10.3389/fnene.2014.00001

Ejemplares similares