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Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study
OBJECTIVE: To compare the effectiveness of vacuum-assisted closure (VAC) versus conventional dressings in the healing of diabetic foot ulcerations (DFUs) in terms of healing rate (time to prepare the wound for closure either spontaneously or by surgery), safety, and patient satisfaction. METHODS: Ra...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Co-Action Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982118/ https://www.ncbi.nlm.nih.gov/pubmed/24765245 http://dx.doi.org/10.3402/dfa.v5.23345 |
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author | Lone, Ali M. Zaroo, Mohd I. Laway, Bashir A. Pala, Nazir A. Bashir, Sheikh A. Rasool, Altaf |
author_facet | Lone, Ali M. Zaroo, Mohd I. Laway, Bashir A. Pala, Nazir A. Bashir, Sheikh A. Rasool, Altaf |
author_sort | Lone, Ali M. |
collection | PubMed |
description | OBJECTIVE: To compare the effectiveness of vacuum-assisted closure (VAC) versus conventional dressings in the healing of diabetic foot ulcerations (DFUs) in terms of healing rate (time to prepare the wound for closure either spontaneously or by surgery), safety, and patient satisfaction. METHODS: Randomized case–control study enrolling 56 patients, divided into two groups. Group A (patients treated with VAC) and Group B (patients treated with conventional dressings), with an equal number of patients in each group. DFUs were treated until wound closure, either spontaneously, surgically, or until completion of the 8-week period. RESULTS: Granulation tissue appeared in 26 (92.85%) patients by the end of Week 2 in Group A, while it appeared in 15 (53.57%) patients by that time in Group B. 100% granulation was achieved in 21 (77.78%) patients by the end of Week 5 in Group A as compared to only 10 (40%) patients by that time in Group B. Patients in Group A had fewer number of positive blood cultures, secondary amputations and were satisfied with treatment as compared to Group B. CONCLUSION: VAC appears to be more effective, safe, and patient satisfactory compared to conventional dressings for the treatment of DFUs. |
format | Online Article Text |
id | pubmed-3982118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Co-Action Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-39821182014-04-24 Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study Lone, Ali M. Zaroo, Mohd I. Laway, Bashir A. Pala, Nazir A. Bashir, Sheikh A. Rasool, Altaf Diabet Foot Ankle Clinical Research Article OBJECTIVE: To compare the effectiveness of vacuum-assisted closure (VAC) versus conventional dressings in the healing of diabetic foot ulcerations (DFUs) in terms of healing rate (time to prepare the wound for closure either spontaneously or by surgery), safety, and patient satisfaction. METHODS: Randomized case–control study enrolling 56 patients, divided into two groups. Group A (patients treated with VAC) and Group B (patients treated with conventional dressings), with an equal number of patients in each group. DFUs were treated until wound closure, either spontaneously, surgically, or until completion of the 8-week period. RESULTS: Granulation tissue appeared in 26 (92.85%) patients by the end of Week 2 in Group A, while it appeared in 15 (53.57%) patients by that time in Group B. 100% granulation was achieved in 21 (77.78%) patients by the end of Week 5 in Group A as compared to only 10 (40%) patients by that time in Group B. Patients in Group A had fewer number of positive blood cultures, secondary amputations and were satisfied with treatment as compared to Group B. CONCLUSION: VAC appears to be more effective, safe, and patient satisfactory compared to conventional dressings for the treatment of DFUs. Co-Action Publishing 2014-04-08 /pmc/articles/PMC3982118/ /pubmed/24765245 http://dx.doi.org/10.3402/dfa.v5.23345 Text en © 2014 Ali M. Lone et al. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Research Article Lone, Ali M. Zaroo, Mohd I. Laway, Bashir A. Pala, Nazir A. Bashir, Sheikh A. Rasool, Altaf Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study |
title | Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study |
title_full | Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study |
title_fullStr | Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study |
title_full_unstemmed | Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study |
title_short | Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study |
title_sort | vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study |
topic | Clinical Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982118/ https://www.ncbi.nlm.nih.gov/pubmed/24765245 http://dx.doi.org/10.3402/dfa.v5.23345 |
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