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Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study

OBJECTIVE: To compare the effectiveness of vacuum-assisted closure (VAC) versus conventional dressings in the healing of diabetic foot ulcerations (DFUs) in terms of healing rate (time to prepare the wound for closure either spontaneously or by surgery), safety, and patient satisfaction. METHODS: Ra...

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Autores principales: Lone, Ali M., Zaroo, Mohd I., Laway, Bashir A., Pala, Nazir A., Bashir, Sheikh A., Rasool, Altaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982118/
https://www.ncbi.nlm.nih.gov/pubmed/24765245
http://dx.doi.org/10.3402/dfa.v5.23345
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author Lone, Ali M.
Zaroo, Mohd I.
Laway, Bashir A.
Pala, Nazir A.
Bashir, Sheikh A.
Rasool, Altaf
author_facet Lone, Ali M.
Zaroo, Mohd I.
Laway, Bashir A.
Pala, Nazir A.
Bashir, Sheikh A.
Rasool, Altaf
author_sort Lone, Ali M.
collection PubMed
description OBJECTIVE: To compare the effectiveness of vacuum-assisted closure (VAC) versus conventional dressings in the healing of diabetic foot ulcerations (DFUs) in terms of healing rate (time to prepare the wound for closure either spontaneously or by surgery), safety, and patient satisfaction. METHODS: Randomized case–control study enrolling 56 patients, divided into two groups. Group A (patients treated with VAC) and Group B (patients treated with conventional dressings), with an equal number of patients in each group. DFUs were treated until wound closure, either spontaneously, surgically, or until completion of the 8-week period. RESULTS: Granulation tissue appeared in 26 (92.85%) patients by the end of Week 2 in Group A, while it appeared in 15 (53.57%) patients by that time in Group B. 100% granulation was achieved in 21 (77.78%) patients by the end of Week 5 in Group A as compared to only 10 (40%) patients by that time in Group B. Patients in Group A had fewer number of positive blood cultures, secondary amputations and were satisfied with treatment as compared to Group B. CONCLUSION: VAC appears to be more effective, safe, and patient satisfactory compared to conventional dressings for the treatment of DFUs.
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spelling pubmed-39821182014-04-24 Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study Lone, Ali M. Zaroo, Mohd I. Laway, Bashir A. Pala, Nazir A. Bashir, Sheikh A. Rasool, Altaf Diabet Foot Ankle Clinical Research Article OBJECTIVE: To compare the effectiveness of vacuum-assisted closure (VAC) versus conventional dressings in the healing of diabetic foot ulcerations (DFUs) in terms of healing rate (time to prepare the wound for closure either spontaneously or by surgery), safety, and patient satisfaction. METHODS: Randomized case–control study enrolling 56 patients, divided into two groups. Group A (patients treated with VAC) and Group B (patients treated with conventional dressings), with an equal number of patients in each group. DFUs were treated until wound closure, either spontaneously, surgically, or until completion of the 8-week period. RESULTS: Granulation tissue appeared in 26 (92.85%) patients by the end of Week 2 in Group A, while it appeared in 15 (53.57%) patients by that time in Group B. 100% granulation was achieved in 21 (77.78%) patients by the end of Week 5 in Group A as compared to only 10 (40%) patients by that time in Group B. Patients in Group A had fewer number of positive blood cultures, secondary amputations and were satisfied with treatment as compared to Group B. CONCLUSION: VAC appears to be more effective, safe, and patient satisfactory compared to conventional dressings for the treatment of DFUs. Co-Action Publishing 2014-04-08 /pmc/articles/PMC3982118/ /pubmed/24765245 http://dx.doi.org/10.3402/dfa.v5.23345 Text en © 2014 Ali M. Lone et al. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research Article
Lone, Ali M.
Zaroo, Mohd I.
Laway, Bashir A.
Pala, Nazir A.
Bashir, Sheikh A.
Rasool, Altaf
Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study
title Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study
title_full Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study
title_fullStr Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study
title_full_unstemmed Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study
title_short Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study
title_sort vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study
topic Clinical Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982118/
https://www.ncbi.nlm.nih.gov/pubmed/24765245
http://dx.doi.org/10.3402/dfa.v5.23345
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