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NANOG Amplifies STAT3 Activation and They Synergistically Induce the Naive Pluripotent Program
Reprogramming of a differentiated cell back to a naive pluripotent identity is thought to occur by several independent mechanisms. Two such mechanisms include NANOG and activated STAT3 (pSTAT3), known master regulators of naive pluripotency acquisition [1–5]. Here, we investigated the relationship b...
Autores principales: | Stuart, Hannah T., van Oosten, Anouk L., Radzisheuskaya, Aliaksandra, Martello, Graziano, Miller, Anzy, Dietmann, Sabine, Nichols, Jennifer, Silva, José C.R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982126/ https://www.ncbi.nlm.nih.gov/pubmed/24462001 http://dx.doi.org/10.1016/j.cub.2013.12.040 |
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