Anti-Angiogenesis Therapy in the Vx2 Rabbit Cancer Model with a Lipase-cleavable Sn 2 Taxane Phospholipid Prodrug using α(v)β(3)-Targeted Theranostic Nanoparticles

In nanomedicine, the hydrophobic nature of paclitaxel has favored its incorporation into many nanoparticle formulations for anti-cancer chemotherapy. At lower doses taxanes are reported to elicit anti-angiogenic responses. In the present study, the facile synthesis, development and characterization...

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Detalles Bibliográficos
Autores principales: Pan, Dipanjan, Schmieder, Anne H., Wang, Kezheng, Yang, Xiaoxia, Senpan, Angana, Cui, Grace, Killgore, Kendall, Kim, Benjamin, Allen, John S., Zhang, Huiying, Caruthers, Shelton D., Shen, Baozhong, Wickline, Samuel A., Lanza, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982128/
https://www.ncbi.nlm.nih.gov/pubmed/24723979
http://dx.doi.org/10.7150/thno.7581

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