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Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children

This paper provides an overview of insulin-induced hypoglycemia as a triggering factor of cognitive deficit in children with type 1 diabetes mellitus. For this purpose, databases from 1961 to 2013 were used with the objective of detecting the primary publications that address the impact of hypoglyce...

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Autores principales: Rodrigues Vilela, Vanessa, de Castro Ruiz Marques, Any, Schamber, Christiano Rodrigues, Bazotte, Roberto Barbosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982249/
https://www.ncbi.nlm.nih.gov/pubmed/24790575
http://dx.doi.org/10.1155/2014/616534
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author Rodrigues Vilela, Vanessa
de Castro Ruiz Marques, Any
Schamber, Christiano Rodrigues
Bazotte, Roberto Barbosa
author_facet Rodrigues Vilela, Vanessa
de Castro Ruiz Marques, Any
Schamber, Christiano Rodrigues
Bazotte, Roberto Barbosa
author_sort Rodrigues Vilela, Vanessa
collection PubMed
description This paper provides an overview of insulin-induced hypoglycemia as a triggering factor of cognitive deficit in children with type 1 diabetes mellitus. For this purpose, databases from 1961 to 2013 were used with the objective of detecting the primary publications that address the impact of hypoglycemia on cognitive performance of diabetic children. The results obtained from experimental animals were excluded. The majority of studies demonstrated that the cognitive deficit in diabetic children involves multiple factors including duration, intensity, severity, and frequency of hypoglycemia episodes. Additionally, age at the onset of type 1 diabetes also influences the cognitive performance, considering that early inception of the disease is a predisposing factor for severe hypoglycemia. Furthermore, the results suggest that there is a strong correlation between brain damage caused by hypoglycemia and cognitive deterioration. Therefore, a more cautious follow-up and education are needed to impede and treat hypoglycemia in children with diabetes mellitus.
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spelling pubmed-39822492014-04-30 Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children Rodrigues Vilela, Vanessa de Castro Ruiz Marques, Any Schamber, Christiano Rodrigues Bazotte, Roberto Barbosa ScientificWorldJournal Review Article This paper provides an overview of insulin-induced hypoglycemia as a triggering factor of cognitive deficit in children with type 1 diabetes mellitus. For this purpose, databases from 1961 to 2013 were used with the objective of detecting the primary publications that address the impact of hypoglycemia on cognitive performance of diabetic children. The results obtained from experimental animals were excluded. The majority of studies demonstrated that the cognitive deficit in diabetic children involves multiple factors including duration, intensity, severity, and frequency of hypoglycemia episodes. Additionally, age at the onset of type 1 diabetes also influences the cognitive performance, considering that early inception of the disease is a predisposing factor for severe hypoglycemia. Furthermore, the results suggest that there is a strong correlation between brain damage caused by hypoglycemia and cognitive deterioration. Therefore, a more cautious follow-up and education are needed to impede and treat hypoglycemia in children with diabetes mellitus. Hindawi Publishing Corporation 2014-03-23 /pmc/articles/PMC3982249/ /pubmed/24790575 http://dx.doi.org/10.1155/2014/616534 Text en Copyright © 2014 Vanessa Rodrigues Vilela et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Rodrigues Vilela, Vanessa
de Castro Ruiz Marques, Any
Schamber, Christiano Rodrigues
Bazotte, Roberto Barbosa
Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children
title Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children
title_full Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children
title_fullStr Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children
title_full_unstemmed Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children
title_short Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children
title_sort hypoglycemia induced by insulin as a triggering factor of cognitive deficit in diabetic children
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982249/
https://www.ncbi.nlm.nih.gov/pubmed/24790575
http://dx.doi.org/10.1155/2014/616534
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