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Minor Physical Anomalies in Adults with Autism Spectrum Disorder and Healthy Controls
Minor Physical Anomalies (MPAs) are subtle abnormalities of the head, face, and limbs, without significant cosmetic or functional impact to the individual. They are assumed to represent external markers of developmental deviations during foetal life. MPAs have been suggested to indicate severity in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982266/ https://www.ncbi.nlm.nih.gov/pubmed/24782925 http://dx.doi.org/10.1155/2014/743482 |
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author | Manouilenko, Irina Eriksson, Jonna M. Humble, Mats B. Bejerot, Susanne |
author_facet | Manouilenko, Irina Eriksson, Jonna M. Humble, Mats B. Bejerot, Susanne |
author_sort | Manouilenko, Irina |
collection | PubMed |
description | Minor Physical Anomalies (MPAs) are subtle abnormalities of the head, face, and limbs, without significant cosmetic or functional impact to the individual. They are assumed to represent external markers of developmental deviations during foetal life. MPAs have been suggested to indicate severity in mental illness and constitute external markers for atypical brain development. Higher frequencies of MPAs can be found in children with autism. The aims of the present study were to examine the prevalence and patterns of MPAs in adults with autism spectrum disorder (ASD) and to investigate whether MPAs are associated with symptom severity and overall functioning. Fifty adults with ASD and intelligence within the normal range and 53 healthy controls were examined with the Waldrop scale, an instrument for assessing MPAs. Face and feet were photographed enabling blinded assessment. Significant differences between the ASD and the control group were found on the MPA total scores, and also in the craniofacial region scores. Moreover, the shape of the ears was associated with autistic traits, in the ASD group. High MPA total scores were associated with poorer functioning. The findings suggest a link between MPAs, autistic traits, and level of functioning. Assessment of MPAs may assist in the diagnostic procedure of psychiatric disorders. |
format | Online Article Text |
id | pubmed-3982266 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39822662014-04-29 Minor Physical Anomalies in Adults with Autism Spectrum Disorder and Healthy Controls Manouilenko, Irina Eriksson, Jonna M. Humble, Mats B. Bejerot, Susanne Autism Res Treat Clinical Study Minor Physical Anomalies (MPAs) are subtle abnormalities of the head, face, and limbs, without significant cosmetic or functional impact to the individual. They are assumed to represent external markers of developmental deviations during foetal life. MPAs have been suggested to indicate severity in mental illness and constitute external markers for atypical brain development. Higher frequencies of MPAs can be found in children with autism. The aims of the present study were to examine the prevalence and patterns of MPAs in adults with autism spectrum disorder (ASD) and to investigate whether MPAs are associated with symptom severity and overall functioning. Fifty adults with ASD and intelligence within the normal range and 53 healthy controls were examined with the Waldrop scale, an instrument for assessing MPAs. Face and feet were photographed enabling blinded assessment. Significant differences between the ASD and the control group were found on the MPA total scores, and also in the craniofacial region scores. Moreover, the shape of the ears was associated with autistic traits, in the ASD group. High MPA total scores were associated with poorer functioning. The findings suggest a link between MPAs, autistic traits, and level of functioning. Assessment of MPAs may assist in the diagnostic procedure of psychiatric disorders. Hindawi Publishing Corporation 2014 2014-03-24 /pmc/articles/PMC3982266/ /pubmed/24782925 http://dx.doi.org/10.1155/2014/743482 Text en Copyright © 2014 Irina Manouilenko et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Manouilenko, Irina Eriksson, Jonna M. Humble, Mats B. Bejerot, Susanne Minor Physical Anomalies in Adults with Autism Spectrum Disorder and Healthy Controls |
title | Minor Physical Anomalies in Adults with Autism Spectrum Disorder and Healthy Controls |
title_full | Minor Physical Anomalies in Adults with Autism Spectrum Disorder and Healthy Controls |
title_fullStr | Minor Physical Anomalies in Adults with Autism Spectrum Disorder and Healthy Controls |
title_full_unstemmed | Minor Physical Anomalies in Adults with Autism Spectrum Disorder and Healthy Controls |
title_short | Minor Physical Anomalies in Adults with Autism Spectrum Disorder and Healthy Controls |
title_sort | minor physical anomalies in adults with autism spectrum disorder and healthy controls |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982266/ https://www.ncbi.nlm.nih.gov/pubmed/24782925 http://dx.doi.org/10.1155/2014/743482 |
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