Cargando…
Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significan...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982269/ https://www.ncbi.nlm.nih.gov/pubmed/24783207 http://dx.doi.org/10.1155/2014/474905 |
_version_ | 1782311161108103168 |
---|---|
author | Distler, M. Aust, D. Weitz, J. Pilarsky, C. Grützmann, Robert |
author_facet | Distler, M. Aust, D. Weitz, J. Pilarsky, C. Grützmann, Robert |
author_sort | Distler, M. |
collection | PubMed |
description | Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significantly over the last decade, and nowadays we know that mainly three lesions (PanIN, and IPMN, MCN) are responsible for the development of pancreatic cancer. The early detection of these lesions is still challenging but provides the chance to cure patients before they might get an invasive pancreatic carcinoma. This paper focuses on PanIN, IPMN, and MCN lesions and reviews the current level of knowledge and clinical measures. |
format | Online Article Text |
id | pubmed-3982269 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39822692014-04-29 Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN Distler, M. Aust, D. Weitz, J. Pilarsky, C. Grützmann, Robert Biomed Res Int Review Article Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significantly over the last decade, and nowadays we know that mainly three lesions (PanIN, and IPMN, MCN) are responsible for the development of pancreatic cancer. The early detection of these lesions is still challenging but provides the chance to cure patients before they might get an invasive pancreatic carcinoma. This paper focuses on PanIN, IPMN, and MCN lesions and reviews the current level of knowledge and clinical measures. Hindawi Publishing Corporation 2014 2014-03-24 /pmc/articles/PMC3982269/ /pubmed/24783207 http://dx.doi.org/10.1155/2014/474905 Text en Copyright © 2014 M. Distler et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Distler, M. Aust, D. Weitz, J. Pilarsky, C. Grützmann, Robert Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN |
title | Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN |
title_full | Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN |
title_fullStr | Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN |
title_full_unstemmed | Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN |
title_short | Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN |
title_sort | precursor lesions for sporadic pancreatic cancer: panin, ipmn, and mcn |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982269/ https://www.ncbi.nlm.nih.gov/pubmed/24783207 http://dx.doi.org/10.1155/2014/474905 |
work_keys_str_mv | AT distlerm precursorlesionsforsporadicpancreaticcancerpaninipmnandmcn AT austd precursorlesionsforsporadicpancreaticcancerpaninipmnandmcn AT weitzj precursorlesionsforsporadicpancreaticcancerpaninipmnandmcn AT pilarskyc precursorlesionsforsporadicpancreaticcancerpaninipmnandmcn AT grutzmannrobert precursorlesionsforsporadicpancreaticcancerpaninipmnandmcn |