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Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN

Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significan...

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Detalles Bibliográficos
Autores principales: Distler, M., Aust, D., Weitz, J., Pilarsky, C., Grützmann, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982269/
https://www.ncbi.nlm.nih.gov/pubmed/24783207
http://dx.doi.org/10.1155/2014/474905
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author Distler, M.
Aust, D.
Weitz, J.
Pilarsky, C.
Grützmann, Robert
author_facet Distler, M.
Aust, D.
Weitz, J.
Pilarsky, C.
Grützmann, Robert
author_sort Distler, M.
collection PubMed
description Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significantly over the last decade, and nowadays we know that mainly three lesions (PanIN, and IPMN, MCN) are responsible for the development of pancreatic cancer. The early detection of these lesions is still challenging but provides the chance to cure patients before they might get an invasive pancreatic carcinoma. This paper focuses on PanIN, IPMN, and MCN lesions and reviews the current level of knowledge and clinical measures.
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spelling pubmed-39822692014-04-29 Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN Distler, M. Aust, D. Weitz, J. Pilarsky, C. Grützmann, Robert Biomed Res Int Review Article Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significantly over the last decade, and nowadays we know that mainly three lesions (PanIN, and IPMN, MCN) are responsible for the development of pancreatic cancer. The early detection of these lesions is still challenging but provides the chance to cure patients before they might get an invasive pancreatic carcinoma. This paper focuses on PanIN, IPMN, and MCN lesions and reviews the current level of knowledge and clinical measures. Hindawi Publishing Corporation 2014 2014-03-24 /pmc/articles/PMC3982269/ /pubmed/24783207 http://dx.doi.org/10.1155/2014/474905 Text en Copyright © 2014 M. Distler et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Distler, M.
Aust, D.
Weitz, J.
Pilarsky, C.
Grützmann, Robert
Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
title Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
title_full Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
title_fullStr Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
title_full_unstemmed Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
title_short Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
title_sort precursor lesions for sporadic pancreatic cancer: panin, ipmn, and mcn
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982269/
https://www.ncbi.nlm.nih.gov/pubmed/24783207
http://dx.doi.org/10.1155/2014/474905
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