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De-Novo Histoid Hansen Cases

Histoid leprosy is a rare form of multibacillary leprosy with distinct clinical and histopathological features. It is a variant of lepromatous leprosy with a very high bacterial index. It appears in patients as a relapse after dapsone monotherapy, in the presence of dapsone resistance or rarely ‘de-...

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Autores principales: Vora, Rita Vipul, Pilani, Abhishek P, Mehta, Malay J, Chaudhari, Arvind, Patel, Nidhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982350/
https://www.ncbi.nlm.nih.gov/pubmed/24741226
http://dx.doi.org/10.4103/0974-777X.127944
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author Vora, Rita Vipul
Pilani, Abhishek P
Mehta, Malay J
Chaudhari, Arvind
Patel, Nidhi
author_facet Vora, Rita Vipul
Pilani, Abhishek P
Mehta, Malay J
Chaudhari, Arvind
Patel, Nidhi
author_sort Vora, Rita Vipul
collection PubMed
description Histoid leprosy is a rare form of multibacillary leprosy with distinct clinical and histopathological features. It is a variant of lepromatous leprosy with a very high bacterial index. It appears in patients as a relapse after dapsone monotherapy, in the presence of dapsone resistance or rarely ‘de-novo’. It is a matter of concern as we found three cases of de-novo Histoid that too in 3 months from February 2013 to April 2013; in post-global leprosy elimination era. We report three cases presenting with ‘de-novo’ Histoid Hansen's disease, with no history of leprosy or exposure to dapsone/multi-drug therapy, with heavy bacillary index. The above cases proved to be an eye opener to us in more than one senses. We are reporting these cases just to create awareness and avoid misdiagnosis which will help in prompt treatment and avoid its spread as well as avoid complications and deformities associated with it.
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spelling pubmed-39823502014-04-16 De-Novo Histoid Hansen Cases Vora, Rita Vipul Pilani, Abhishek P Mehta, Malay J Chaudhari, Arvind Patel, Nidhi J Glob Infect Dis Case Report Histoid leprosy is a rare form of multibacillary leprosy with distinct clinical and histopathological features. It is a variant of lepromatous leprosy with a very high bacterial index. It appears in patients as a relapse after dapsone monotherapy, in the presence of dapsone resistance or rarely ‘de-novo’. It is a matter of concern as we found three cases of de-novo Histoid that too in 3 months from February 2013 to April 2013; in post-global leprosy elimination era. We report three cases presenting with ‘de-novo’ Histoid Hansen's disease, with no history of leprosy or exposure to dapsone/multi-drug therapy, with heavy bacillary index. The above cases proved to be an eye opener to us in more than one senses. We are reporting these cases just to create awareness and avoid misdiagnosis which will help in prompt treatment and avoid its spread as well as avoid complications and deformities associated with it. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3982350/ /pubmed/24741226 http://dx.doi.org/10.4103/0974-777X.127944 Text en Copyright: © Journal of Global Infectious Diseases http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Vora, Rita Vipul
Pilani, Abhishek P
Mehta, Malay J
Chaudhari, Arvind
Patel, Nidhi
De-Novo Histoid Hansen Cases
title De-Novo Histoid Hansen Cases
title_full De-Novo Histoid Hansen Cases
title_fullStr De-Novo Histoid Hansen Cases
title_full_unstemmed De-Novo Histoid Hansen Cases
title_short De-Novo Histoid Hansen Cases
title_sort de-novo histoid hansen cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982350/
https://www.ncbi.nlm.nih.gov/pubmed/24741226
http://dx.doi.org/10.4103/0974-777X.127944
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