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Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by airway obstruction and inflammation but also accompanied by several extrapulmonary consequences, such as skeletal muscle weakness and osteoporosis. Skeletal muscle weakness is of major concern, since it leads to poor fun...

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Detalles Bibliográficos
Autores principales: Cielen, Nele, Maes, Karen, Gayan-Ramirez, Ghislaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982416/
https://www.ncbi.nlm.nih.gov/pubmed/24783225
http://dx.doi.org/10.1155/2014/965764
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author Cielen, Nele
Maes, Karen
Gayan-Ramirez, Ghislaine
author_facet Cielen, Nele
Maes, Karen
Gayan-Ramirez, Ghislaine
author_sort Cielen, Nele
collection PubMed
description Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by airway obstruction and inflammation but also accompanied by several extrapulmonary consequences, such as skeletal muscle weakness and osteoporosis. Skeletal muscle weakness is of major concern, since it leads to poor functional capacity, impaired health status, increased healthcare utilization, and even mortality, independently of lung function. Osteoporosis leads to fractures and is associated with increased mortality, functional decline, loss of quality of life, and need for institutionalization. Therefore, the presence of the combination of these comorbidities will have a negative impact on daily life in patients with COPD. In this review, we will focus on these two comorbidities, their prevalence in COPD, combined risk factors, and pathogenesis. We will try to prove the clustering of these comorbidities and discuss possible preventive or therapeutic strategies.
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spelling pubmed-39824162014-04-29 Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease Cielen, Nele Maes, Karen Gayan-Ramirez, Ghislaine Biomed Res Int Review Article Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by airway obstruction and inflammation but also accompanied by several extrapulmonary consequences, such as skeletal muscle weakness and osteoporosis. Skeletal muscle weakness is of major concern, since it leads to poor functional capacity, impaired health status, increased healthcare utilization, and even mortality, independently of lung function. Osteoporosis leads to fractures and is associated with increased mortality, functional decline, loss of quality of life, and need for institutionalization. Therefore, the presence of the combination of these comorbidities will have a negative impact on daily life in patients with COPD. In this review, we will focus on these two comorbidities, their prevalence in COPD, combined risk factors, and pathogenesis. We will try to prove the clustering of these comorbidities and discuss possible preventive or therapeutic strategies. Hindawi Publishing Corporation 2014 2014-03-25 /pmc/articles/PMC3982416/ /pubmed/24783225 http://dx.doi.org/10.1155/2014/965764 Text en Copyright © 2014 Nele Cielen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Cielen, Nele
Maes, Karen
Gayan-Ramirez, Ghislaine
Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease
title Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease
title_full Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease
title_fullStr Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease
title_full_unstemmed Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease
title_short Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease
title_sort musculoskeletal disorders in chronic obstructive pulmonary disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982416/
https://www.ncbi.nlm.nih.gov/pubmed/24783225
http://dx.doi.org/10.1155/2014/965764
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