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Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by airway obstruction and inflammation but also accompanied by several extrapulmonary consequences, such as skeletal muscle weakness and osteoporosis. Skeletal muscle weakness is of major concern, since it leads to poor fun...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982416/ https://www.ncbi.nlm.nih.gov/pubmed/24783225 http://dx.doi.org/10.1155/2014/965764 |
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author | Cielen, Nele Maes, Karen Gayan-Ramirez, Ghislaine |
author_facet | Cielen, Nele Maes, Karen Gayan-Ramirez, Ghislaine |
author_sort | Cielen, Nele |
collection | PubMed |
description | Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by airway obstruction and inflammation but also accompanied by several extrapulmonary consequences, such as skeletal muscle weakness and osteoporosis. Skeletal muscle weakness is of major concern, since it leads to poor functional capacity, impaired health status, increased healthcare utilization, and even mortality, independently of lung function. Osteoporosis leads to fractures and is associated with increased mortality, functional decline, loss of quality of life, and need for institutionalization. Therefore, the presence of the combination of these comorbidities will have a negative impact on daily life in patients with COPD. In this review, we will focus on these two comorbidities, their prevalence in COPD, combined risk factors, and pathogenesis. We will try to prove the clustering of these comorbidities and discuss possible preventive or therapeutic strategies. |
format | Online Article Text |
id | pubmed-3982416 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39824162014-04-29 Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease Cielen, Nele Maes, Karen Gayan-Ramirez, Ghislaine Biomed Res Int Review Article Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by airway obstruction and inflammation but also accompanied by several extrapulmonary consequences, such as skeletal muscle weakness and osteoporosis. Skeletal muscle weakness is of major concern, since it leads to poor functional capacity, impaired health status, increased healthcare utilization, and even mortality, independently of lung function. Osteoporosis leads to fractures and is associated with increased mortality, functional decline, loss of quality of life, and need for institutionalization. Therefore, the presence of the combination of these comorbidities will have a negative impact on daily life in patients with COPD. In this review, we will focus on these two comorbidities, their prevalence in COPD, combined risk factors, and pathogenesis. We will try to prove the clustering of these comorbidities and discuss possible preventive or therapeutic strategies. Hindawi Publishing Corporation 2014 2014-03-25 /pmc/articles/PMC3982416/ /pubmed/24783225 http://dx.doi.org/10.1155/2014/965764 Text en Copyright © 2014 Nele Cielen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Cielen, Nele Maes, Karen Gayan-Ramirez, Ghislaine Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease |
title | Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease |
title_full | Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease |
title_fullStr | Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease |
title_full_unstemmed | Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease |
title_short | Musculoskeletal Disorders in Chronic Obstructive Pulmonary Disease |
title_sort | musculoskeletal disorders in chronic obstructive pulmonary disease |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982416/ https://www.ncbi.nlm.nih.gov/pubmed/24783225 http://dx.doi.org/10.1155/2014/965764 |
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