Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects

Owing to the potential use for real personalized genome sequencing, DNA sequencing with solid-state nanopores has been investigated intensively in recent time. However, the area still confronts problems and challenges. In this work, we present a brief overview of computational studies of key issues...

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Detalles Bibliográficos
Autores principales: Liang, Lijun, Wang, Qi, Ågren, Hans, Tu, Yaoquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982512/
https://www.ncbi.nlm.nih.gov/pubmed/24790974
http://dx.doi.org/10.3389/fchem.2014.00005
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author Liang, Lijun
Wang, Qi
Ågren, Hans
Tu, Yaoquan
author_facet Liang, Lijun
Wang, Qi
Ågren, Hans
Tu, Yaoquan
author_sort Liang, Lijun
collection PubMed
description Owing to the potential use for real personalized genome sequencing, DNA sequencing with solid-state nanopores has been investigated intensively in recent time. However, the area still confronts problems and challenges. In this work, we present a brief overview of computational studies of key issues in DNA sequencing with solid-state nanopores by addressing the progress made in the last few years. We also highlight future challenges and prospects for DNA sequencing using this technology.
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spelling pubmed-39825122014-04-30 Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects Liang, Lijun Wang, Qi Ågren, Hans Tu, Yaoquan Front Chem Chemistry Owing to the potential use for real personalized genome sequencing, DNA sequencing with solid-state nanopores has been investigated intensively in recent time. However, the area still confronts problems and challenges. In this work, we present a brief overview of computational studies of key issues in DNA sequencing with solid-state nanopores by addressing the progress made in the last few years. We also highlight future challenges and prospects for DNA sequencing using this technology. Frontiers Media S.A. 2014-02-21 /pmc/articles/PMC3982512/ /pubmed/24790974 http://dx.doi.org/10.3389/fchem.2014.00005 Text en Copyright © 2014 Liang, Wang, Ågren and Tu. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Liang, Lijun
Wang, Qi
Ågren, Hans
Tu, Yaoquan
Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects
title Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects
title_full Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects
title_fullStr Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects
title_full_unstemmed Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects
title_short Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects
title_sort computational studies of dna sequencing with solid-state nanopores: key issues and future prospects
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982512/
https://www.ncbi.nlm.nih.gov/pubmed/24790974
http://dx.doi.org/10.3389/fchem.2014.00005
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