Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in Drosophila

We and others recently demonstrated that the readily programmable CRISPR/Cas9 system can be used to edit the Drosophila genome. However, most applications to date have relied on aberrant DNA repair to stochastically generate frameshifting indels and adoption has been limited by a lack of tools for e...

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Detalles Bibliográficos
Autores principales: Gratz, Scott J., Ukken, Fiona P., Rubinstein, C. Dustin, Thiede, Gene, Donohue, Laura K., Cummings, Alexander M., O’Connor-Giles, Kate M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982687/
https://www.ncbi.nlm.nih.gov/pubmed/24478335
http://dx.doi.org/10.1534/genetics.113.160713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982687/
https://www.ncbi.nlm.nih.gov/pubmed/24478335
http://dx.doi.org/10.1534/genetics.113.160713

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