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A novel NSAID derivative, phospho-ibuprofen, prevents AOM-induced colon cancer in rats

The cancer chemopreventive properties and gastrointestinal toxicity of ibuprofen are well documented. Modification of existing NSAIDs has improved on the chemopreventive efficacy of this agent and reduced its toxicity. In this study, ibuprofen and a modified derivative (phospho-modified ibuprofen or...

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Detalles Bibliográficos
Autores principales: OUYANG, NENGTAI, JI, PING, WILLIAMS, JENNIE L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982714/
https://www.ncbi.nlm.nih.gov/pubmed/23291777
http://dx.doi.org/10.3892/ijo.2012.1756