Positioning of APOBEC3G/F Mutational Hotspots in the Human Immunodeficiency Virus Genome Favors Reduced Recognition by CD8(+) T Cells

Due to constitutive expression in cells targeted by human immunodeficiency virus (HIV), and immediate mode of viral restriction upon HIV entry into the host cell, APOBEC3G (A3G) and APOBEC3F (A3F) have been considered primarily as agents of innate immunity. Recent bioinformatic and mouse model studi...

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Detalles Bibliográficos
Autores principales: Monajemi, Mahdis, Woodworth, Claire F., Zipperlen, Katrin, Gallant, Maureen, Grant, Michael D., Larijani, Mani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982959/
https://www.ncbi.nlm.nih.gov/pubmed/24722422
http://dx.doi.org/10.1371/journal.pone.0093428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982959/
https://www.ncbi.nlm.nih.gov/pubmed/24722422
http://dx.doi.org/10.1371/journal.pone.0093428

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