Effects of Calibration Approaches on the Accuracy for LC–MS Targeted Quantification of Therapeutic Protein

[Image: see text] LC–MS provides a promising alternative to ligand-binding assays for quantification of therapeutic proteins and biomarkers. As LC–MS methodology is based on the analysis of proteolytic peptides, calibration approaches utilizing various calibrators and internal standards (I.S.) have...

Descripción completa

Detalles Bibliográficos
Autores principales: Nouri-Nigjeh, Eslam, Zhang, Ming, Ji, Tao, Yu, Haoying, An, Bo, Duan, Xiaotao, Balthasar, Joseph, Johnson, Robert W., Qu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982980/
https://www.ncbi.nlm.nih.gov/pubmed/24611550
http://dx.doi.org/10.1021/ac5001477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982980/
https://www.ncbi.nlm.nih.gov/pubmed/24611550
http://dx.doi.org/10.1021/ac5001477

Ejemplares similares