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Effects of Calibration Approaches on the Accuracy for LC–MS Targeted Quantification of Therapeutic Protein

[Image: see text] LC–MS provides a promising alternative to ligand-binding assays for quantification of therapeutic proteins and biomarkers. As LC–MS methodology is based on the analysis of proteolytic peptides, calibration approaches utilizing various calibrators and internal standards (I.S.) have...

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Detalles Bibliográficos
Autores principales: Nouri-Nigjeh, Eslam, Zhang, Ming, Ji, Tao, Yu, Haoying, An, Bo, Duan, Xiaotao, Balthasar, Joseph, Johnson, Robert W., Qu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982980/
https://www.ncbi.nlm.nih.gov/pubmed/24611550
http://dx.doi.org/10.1021/ac5001477

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