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Effects of Calibration Approaches on the Accuracy for LC–MS Targeted Quantification of Therapeutic Protein
[Image: see text] LC–MS provides a promising alternative to ligand-binding assays for quantification of therapeutic proteins and biomarkers. As LC–MS methodology is based on the analysis of proteolytic peptides, calibration approaches utilizing various calibrators and internal standards (I.S.) have...
Autores principales: | Nouri-Nigjeh, Eslam, Zhang, Ming, Ji, Tao, Yu, Haoying, An, Bo, Duan, Xiaotao, Balthasar, Joseph, Johnson, Robert W., Qu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982980/ https://www.ncbi.nlm.nih.gov/pubmed/24611550 http://dx.doi.org/10.1021/ac5001477 |
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