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Quantification of Therapeutic miRNA Mimics in Whole Blood from Nonhuman Primates
[Image: see text] MRX34, a microRNA (miRNA)-based therapy for cancer, has recently entered clinical trials as the first clinical candidate in its class. It is a liposomal nanoparticle loaded with a synthetic mimic of the tumor suppressor miRNA miR-34a as the active pharmaceutical ingredient. To unde...
Autores principales: | Kelnar, Kevin, Peltier, Heidi J., Leatherbury, Neil, Stoudemire, Jay, Bader, Andreas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982984/ https://www.ncbi.nlm.nih.gov/pubmed/24397447 http://dx.doi.org/10.1021/ac403044t |
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