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Regulation of the epithelial Ca(2+) channel TRPV5 by reversible histidine phosphorylation mediated by NDPK-B and PHPT1

The kidney, together with bone and intestine, plays a crucial role in maintaining whole-body calcium (Ca(2+)) homoeostasis, which is primarily mediated by altering the reabsorption of Ca(2+) filtered by the glomerulus. The transient receptor potential-vanilloid-5 (TRPV5) channel protein forms a six-...

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Detalles Bibliográficos
Autores principales: Cai, Xinjiang, Srivastava, Shekhar, Surindran, Sheena, Li, Zhai, Skolnik, Edward Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982990/
https://www.ncbi.nlm.nih.gov/pubmed/24523290
http://dx.doi.org/10.1091/mbc.E13-04-0180