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The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

Membrane fusion is generally controlled by Rabs, soluble N-ethylmaleimide–sensitive factor attachment protein receptors (SNAREs), and tethering complexes. Syntaxin 17 (STX17) was recently identified as the autophagosomal SNARE required for autophagosome–lysosome fusion in mammals and Drosophila. In...

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Detalles Bibliográficos
Autores principales:	Jiang, Peidu, Nishimura, Taki, Sakamaki, Yuriko, Itakura, Eisuke, Hatta, Tomohisa, Natsume, Tohru, Mizushima, Noboru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982997/ https://www.ncbi.nlm.nih.gov/pubmed/24554770 http://dx.doi.org/10.1091/mbc.E13-08-0447

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