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Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform
[Image: see text] Nucleic acid aptamers function as versatile sensing and targeting agents for analytical, diagnostic, therapeutic, and gene-regulatory applications, but their limited characterization and functional validation have hindered their broader implementation. We report the development of...
Autores principales: | Chang, Andrew L., McKeague, Maureen, Liang, Joe C., Smolke, Christina D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983011/ https://www.ncbi.nlm.nih.gov/pubmed/24548121 http://dx.doi.org/10.1021/ac5001527 |
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