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Atomistic Picture for the Folding Pathway of a Hybrid-1 Type Human Telomeric DNA G-quadruplex

In this work we studied the folding process of the hybrid-1 type human telomeric DNA G-quadruplex with solvent and [Image: see text] ions explicitly modeled. Enabled by the powerful bias-exchange metadynamics and large-scale conventional molecular dynamic simulations, the free energy landscape of th...

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Detalles Bibliográficos
Autores principales:	Bian, Yunqiang, Tan, Cheng, Wang, Jun, Sheng, Yuebiao, Zhang, Jian, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983051/ https://www.ncbi.nlm.nih.gov/pubmed/24722458 http://dx.doi.org/10.1371/journal.pcbi.1003562

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