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The FAD Cofactor of RebC Shifts to an IN Conformation upon Flavin Reduction(,)

[Image: see text] RebC is a putative flavin hydroxylase functioning together with RebP to carry out a key step in the biosynthesis of rebeccamycin. To probe the mechanism of flavin-based chemistry in RebC, we solved the structure of RebC with reduced flavin. Upon flavin reduction, the RebC crystal u...

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Detalles Bibliográficos
Autores principales:	Ryan, Katherine S., Chakraborty, Sumita, Howard-Jones, Annaleise R., Walsh, Christopher T., Ballou, David P., Drennan, Catherine L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2008
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983088/ https://www.ncbi.nlm.nih.gov/pubmed/19035832 http://dx.doi.org/10.1021/bi801229w

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