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Gonadotropin-Releasing Hormone Agonists Sensitize, and Resensitize, Prostate Cancer Cells to Docetaxel in a p53-Dependent Manner
Gonadotropin-releasing hormone (GnRH) receptors are expressed in prostate cancer, specifically in the most aggressive stage of the tumor (castration-resistant prostate cancer, CRPC) for which the standard treatment, docetaxel-based chemotherapy, can only improve the median survival time by few month...
Autores principales: | Moretti, Roberta M., Marelli, Marina Montagnani, Taylor, Deanne M., Martini, Paolo G. V., Marzagalli, Monica, Limonta, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983111/ https://www.ncbi.nlm.nih.gov/pubmed/24722580 http://dx.doi.org/10.1371/journal.pone.0093713 |
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